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Gene: HNRNPH2 (heterogeneous nuclear ribonucleoprotein H2) Homo sapiens
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Symbol: HNRNPH2
Name: heterogeneous nuclear ribonucleoprotein H2
Description: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed. [provided by RefSeq, Jan 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FTP-3; FTP3; heterogeneous nuclear ribonucleoprotein H'; heterogeneous nuclear ribonucleoprotein H-prime; heterogeneous nuclear ribonucleoprotein H2 (H'); hnRNP H'; hnRNP H2; hnRNPH'; HNRPH'; HNRPH2; MRXSB; NRPH2
Orthologs:
Mus musculus (house mouse) : Hnrnph2 (heterogeneous nuclear ribonucleoprotein H2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hnrnph2 (heterogeneous nuclear ribonucleoprotein H2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hnrnph2 (heterogeneous nuclear ribonucleoprotein H2)
Pan paniscus (bonobo/pygmy chimpanzee) : HNRNPH2 (heterogeneous nuclear ribonucleoprotein H2)
Canis lupus familiaris (dog) : HNRNPH2 (heterogeneous nuclear ribonucleoprotein H2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hnrnph2 (heterogeneous nuclear ribonucleoprotein H2)
Sus scrofa (pig) : HNRNPH2 (heterogeneous nuclear ribonucleoprotein H2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X101,408,133 - 101,414,140 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X100,663,121 - 100,669,128 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X100,549,847 - 100,555,777 (+)NCBINCBI36hg18NCBI36
CeleraX101,182,649 - 101,188,579 (+)NCBI
Cytogenetic MapXq22.1NCBI
HuRefX90,469,009 - 90,475,016 (+)NCBIHuRef
CHM1_1X100,556,599 - 100,562,666 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on HNRNPH2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605724
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-08-06
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.