Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: FOXA2 (forkhead box A2) Homo sapiens
Analyze
Symbol: FOXA2
Name: forkhead box A2
CRRD ID: 1605726
Description: Exhibits DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including dopaminergic neuron differentiation; negative regulation of epithelial to mesenchymal transition; and regulation of transcription, DNA-templated. Localizes to cell junction and nucleoplasm. Implicated in type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: forkhead box protein A2; hepatic nuclear factor-3-beta; hepatocyte nuclear factor 3, beta; hepatocyte nuclear factor 3-beta; HNF-3-beta; HNF-3B; HNF3B; MGC19807; TCF-3B; TCF3B; transcription factor 3B
Orthologs:
Mus musculus (house mouse) : Foxa2 (forkhead box A2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Foxa2 (forkhead box A2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Foxa2 (forkhead box A2)
Pan paniscus (bonobo/pygmy chimpanzee) : FOXA2 (forkhead box A2)
Canis lupus familiaris (dog) : FOXA2 (forkhead box A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxa2 (forkhead box A2)
Sus scrofa (pig) : FOXA2 (forkhead box A2)
Chlorocebus sabaeus (African green monkey) : FOXA2 (forkhead box A2)
Heterocephalus glaber (naked mole-rat) : Foxa2 (forkhead box A2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2022,581,005 - 22,585,455 (-)EnsemblGRCh38hg38GRCh38
GRCh382022,580,998 - 22,585,490 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372022,561,642 - 22,566,101 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362022,509,823 - 22,514,102 (-)NCBINCBI36hg18NCBI36
Celera2022,635,086 - 22,639,544 (-)NCBI
Cytogenetic Map20p11.21NCBI
HuRef2022,523,682 - 22,527,950 (-)NCBIHuRef
CHM1_12022,562,253 - 22,566,723 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on FOXA2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605726
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.