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Gene: TSC22D3 (TSC22 domain family member 3) Homo sapiens
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Symbol: TSC22D3
Name: TSC22 domain family member 3
Description: This gene encodes the anti-inflammatory protein glucocorticoid (GC)-induced leucine zipper. Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid. This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor κB. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: delta sleep inducing peptide, immunoreactor; delta sleep-inducing peptide immunoreactor; DIP; DKFZp313A1123; DSIP-immunoreactive leucine zipper protein; DSIP-immunoreactive peptide; DSIPI; GILZ; glucocorticoid-induced leucine zipper protein; hDIP; TSC-22 related protein; TSC-22-like protein; TSC-22-related protein; TSC-22R; TSC22 domain family protein 3; TSC22 domain family, member 3
Orthologs:
Mus musculus (house mouse) : Tsc22d3 (TSC22 domain family, member 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tsc22d3 (TSC22 domain family, member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tsc22d3 (TSC22 domain family member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TSC22D3 (TSC22 domain family member 3)
Canis lupus familiaris (dog) : TSC22D3 (TSC22 domain family member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tsc22d3 (TSC22 domain family member 3)
Sus scrofa (pig) : TSC22D3 (TSC22 domain family member 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X107,713,221 - 107,777,329 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X106,956,451 - 107,020,559 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X106,843,107 - 106,905,673 (-)NCBINCBI36hg18NCBI36
CeleraX107,427,403 - 107,489,966 (-)NCBI
Cytogenetic MapXq22.3NCBI
HuRefX96,580,831 - 96,643,067 (-)NCBIHuRef
CHM1_1X106,867,386 - 106,930,124 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TSC22D3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605734
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.