Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: TSC22D3 (TSC22 domain family member 3) Homo sapiens
Symbol: TSC22D3
Name: TSC22 domain family member 3
Description: This gene encodes the anti-inflammatory protein glucocorticoid (GC)-induced leucine zipper. Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid. This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor κB. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: delta sleep inducing peptide, immunoreactor; delta sleep-inducing peptide immunoreactor; DIP; DKFZp313A1123; DSIP-immunoreactive leucine zipper protein; DSIP-immunoreactive peptide; DSIPI; GILZ; glucocorticoid-induced leucine zipper protein; hDIP; TSC-22 related protein; TSC-22-like protein; TSC-22-related protein; TSC-22R; TSC22 domain family protein 3; TSC22 domain family, member 3
Mus musculus (house mouse) : Tsc22d3 (TSC22 domain family, member 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tsc22d3 (TSC22 domain family, member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tsc22d3 (TSC22 domain family member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TSC22D3 (TSC22 domain family member 3)
Canis lupus familiaris (dog) : TSC22D3 (TSC22 domain family member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tsc22d3 (TSC22 domain family member 3)
Sus scrofa (pig) : TSC22D3 (TSC22 domain family member 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X107,713,221 - 107,777,329 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X106,956,451 - 107,020,559 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X106,843,107 - 106,905,673 (-)NCBINCBI36hg18NCBI36
CeleraX107,427,403 - 107,489,966 (-)NCBI
Cytogenetic MapXq22.3NCBI
HuRefX96,580,831 - 96,643,067 (-)NCBIHuRef
CHM1_1X106,867,386 - 106,930,124 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TSC22D3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605734
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.