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Gene: WDR59 (WD repeat domain 59) Homo sapiens
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Symbol: WDR59
Name: WD repeat domain 59
Description: Involved in cellular response to amino acid starvation and positive regulation of TOR signaling. Localizes to the GATOR2 complex and lysosomal membrane; PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; 4,4'-sulfonyldiphenol; arsane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CDW12; CDw12 antigen; FLJ12270; FP977; GATOR complex protein WDR59; MGC11230; p90-120; WD repeat-containing protein 59
Orthologs:
Mus musculus (house mouse) : Wdr59 (WD repeat domain 59)  MGI  Alliance
Rattus norvegicus (Norway rat) : Wdr59 (WD repeat domain 59)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wdr59 (WD repeat domain 59)
Pan paniscus (bonobo/pygmy chimpanzee) : WDR59 (WD repeat domain 59)
Canis lupus familiaris (dog) : WDR59 (WD repeat domain 59)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101966958 (GATOR complex protein WDR59)
Sus scrofa (pig) : WDR59 (WD repeat domain 59)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381674,871,362 - 74,985,146 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371674,907,468 - 75,019,026 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361673,464,972 - 73,576,518 (-)NCBINCBI36hg18NCBI36
Celera1659,200,469 - 59,311,988 (-)NCBI
Cytogenetic Map16q23.1NCBI
HuRef1660,657,825 - 60,769,973 (-)NCBIHuRef
CHM1_11676,319,729 - 76,431,261 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on WDR59
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605950
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.