Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: TMBIM1 (transmembrane BAX inhibitor motif containing 1) Homo sapiens
Analyze
Symbol: TMBIM1
Name: transmembrane BAX inhibitor motif containing 1
Description: Exhibits death receptor binding activity. Involved in negative regulation of Fas signaling pathway; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; and negative regulation of protein localization to plasma membrane. Localizes to Golgi apparatus; endosome membrane; and lysosomal membrane; INTERACTS WITH aflatoxin B1; aflatoxin B2; arsenous acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LFG3; MST100; MSTP100; PP1201; protein lifeguard 3; protein RECS1 homolog; RECS1; transmembrane BAX inhibitor motif-containing protein 1
Orthologs:
Mus musculus (house mouse) : Tmbim1 (transmembrane BAX inhibitor motif containing 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tmbim1 (transmembrane BAX inhibitor motif containing 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmbim1 (transmembrane BAX inhibitor motif containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TMBIM1 (transmembrane BAX inhibitor motif containing 1)
Canis lupus familiaris (dog) : TMBIM1 (transmembrane BAX inhibitor motif containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmbim1 (transmembrane BAX inhibitor motif containing 1)
Sus scrofa (pig) : TMBIM1 (transmembrane BAX inhibitor motif containing 1)
Chlorocebus sabaeus (African green monkey) : TMBIM1 (transmembrane BAX inhibitor motif containing 1)
Heterocephalus glaber (naked mole-rat) : Tmbim1 (transmembrane BAX inhibitor motif containing 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl2218,274,197 - 218,292,586 (-)EnsemblGRCh38hg38GRCh38
GRCh382218,274,192 - 218,292,577 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372219,138,917 - 219,157,280 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362218,847,161 - 218,865,524 (-)NCBINCBI36hg18NCBI36
Celera2212,905,492 - 212,923,864 (-)NCBI
Cytogenetic Map2q35ENTREZGENE
HuRef2210,992,006 - 211,010,384 (-)NCBIHuRef
CHM1_12219,145,396 - 219,163,784 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on TMBIM1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605964
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.