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Gene: PHRF1 (PHD and ring finger domains 1) Homo sapiens
Symbol: PHRF1
Name: PHD and ring finger domains 1
Description: Predicted to have RNA polymerase binding activity. Predicted to be involved in mRNA processing and transcription by RNA polymerase II. Localizes to membrane; INTERACTS WITH 2-hydroxypropanoic acid; aflatoxin B2; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CTD binding SR like protein rA9; CTD-binding SR-like protein rA9; KIAA1542; PHD and RING finger domain-containing protein 1; PPP1R125; RNF221
Mus musculus (house mouse) : Phrf1 (PHD and ring finger domains 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Phrf1 (PHD and ring finger domains 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Phrf1 (PHD and ring finger domains 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PHRF1 (PHD and ring finger domains 1)
Canis lupus familiaris (dog) : PHRF1 (PHD and ring finger domains 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Phrf1 (PHD and ring finger domains 1)
Sus scrofa (pig) : PHRF1 (PHD and ring finger domains 1)
Chlorocebus sabaeus (African green monkey) : PHRF1 (PHD and ring finger domains 1)
Heterocephalus glaber (naked mole-rat) : Phrf1 (PHD and ring finger domains 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl11576,470 - 612,222 (+)EnsemblGRCh38hg38GRCh38
GRCh3811576,446 - 612,222 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711576,226 - 612,222 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611566,486 - 602,220 (+)NCBINCBI36hg18NCBI36
Celera11639,140 - 677,368 (+)NCBI
Cytogenetic Map11p15.5NCBI
HuRef11371,145 - 427,527 (+)NCBIHuRef
CHM1_111575,367 - 611,262 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PHRF1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605972
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.