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Gene: ATM (ATM serine/threonine kinase) Homo sapiens
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Symbol: ATM
Name: ATM serine/threonine kinase
Description: Exhibits identical protein binding activity; kinase activity; and protein N-terminus binding activity. Involved in several processes, including cellular response to ionizing radiation; negative regulation of cell cycle; and regulation of telomere maintenance. Localizes to the DNA repair complex; nucleolus; and nucleoplasm. Colocalizes with the chromosome, telomeric region. Implicated in Parkinson's disease; ataxia telangiectasia; breast cancer; endometrial cancer; and pancreatic cancer. Biomarker of Alzheimer's disease; breast carcinoma; and prostate carcinoma in situ.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A-T mutated; AT mutated; AT1; ATA; ataxia telangiectasia mutated; ataxia telangiectasia mutated (includes complementation groups A, C and D); ATC; ATD; ATDC; ATE; DKFZp781A0353; human phosphatidylinositol 3-kinase homolog; MGC74674; serine-protein kinase ATM; TEL1; TEL1, telomere maintenance 1, homolog; TELO1
Orthologs:
Mus musculus (house mouse) : Atm (ataxia telangiectasia mutated)  MGI  Alliance
Rattus norvegicus (Norway rat) : Atm (ATM serine/threonine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atm (ATM serine/threonine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : ATM (ATM serine/threonine kinase)
Canis lupus familiaris (dog) : ATM (ATM serine/threonine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atm (ATM serine/threonine kinase)
Sus scrofa (pig) : ATM (ATM serine/threonine kinase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811108,222,484 - 108,369,102 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711108,093,559 - 108,239,829 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611107,598,769 - 107,745,036 (+)NCBINCBI36hg18NCBI36
Celera11105,248,510 - 105,394,764 (+)NCBI
Cytogenetic Map11q22.3NCBI
HuRef11104,019,183 - 104,165,444 (+)NCBIHuRef
CHM1_111107,976,660 - 108,122,959 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model