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Gene: ZNF746 (zinc finger protein 746) Homo sapiens
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Symbol: ZNF746
Name: zinc finger protein 746
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and ubiquitin protein ligase binding activity. Involved in negative regulation of transcription by RNA polymerase II; positive regulation of neuron death; and positive regulation of transcription by RNA polymerase II. Localizes to the cytoplasm; INTERACTS WITH 2-hydroxypropanoic acid; 2-methylcholine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ31413; PARIS; parkin interacting substrate; parkin-interacting substrate; parkin-interacting sustrate
Orthologs:
Mus musculus (house mouse) : Zfp746 (zinc finger protein 746)  MGI  Alliance
Rattus norvegicus (Norway rat) : Zfp746 (zinc finger protein 746)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Znf746 (zinc finger protein 746)
Pan paniscus (bonobo/pygmy chimpanzee) : ZNF746 (zinc finger protein 746)
Canis lupus familiaris (dog) : ZNF746 (zinc finger protein 746)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Znf746 (zinc finger protein 746)
Sus scrofa (pig) : ZNF746 (zinc finger protein 746)
more info ...
Related Pseudogenes: ZNF767P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387149,472,696 - 149,497,832 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377149,169,884 - 149,194,928 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367148,800,818 - 148,825,727 (-)NCBINCBI36hg18NCBI36
Celera7143,839,142 - 143,864,156 (-)NCBI
Cytogenetic Map7q36.1NCBI
HuRef7143,246,332 - 143,271,282 (-)NCBIHuRef
CHM1_17149,178,475 - 149,203,485 (-)NCBICHM1_1
CRA_TCAGchr7v27148,507,917 - 148,532,930 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on ZNF746
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1606138
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.