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Gene: MAVS (mitochondrial antiviral signaling protein) Homo sapiens
Symbol: MAVS
Name: mitochondrial antiviral signaling protein
Description: This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CARD adapter inducing interferon beta; CARD adapter inducing interferon-beta; CARD adaptor inducing IFN-beta; CARDIF; DKFZp547C224; DKFZp666M015; FLJ27482; FLJ31698; FLJ35386; FLJ38051; FLJ41962; IFN-B promoter stimulator 1; interferon beta promoter stimulator protein 1; interferon-beta promoter stimulator protein 1; IPS-1; IPS1; KIAA1271; MGC3260; mitochondrial anti-viral signaling protein; mitochondrial antiviral-signaling protein; putative NF-kappa-B-activating protein 031N; virus-induced signaling adapter variant 1b; virus-induced signaling adaptor; virus-induced signaling adaptor variant 1a; virus-induced-signaling adapter; VISA
Mus musculus (house mouse) : Mavs (mitochondrial antiviral signaling protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mavs (mitochondrial antiviral signaling protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mavs (mitochondrial antiviral signaling protein)
Pan paniscus (bonobo/pygmy chimpanzee) : MAVS (mitochondrial antiviral signaling protein)
Canis lupus familiaris (dog) : MAVS (mitochondrial antiviral signaling protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mavs (mitochondrial antiviral signaling protein)
Sus scrofa (pig) : MAVS (mitochondrial antiviral signaling protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38203,846,799 - 3,876,123 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37203,827,446 - 3,856,770 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36203,775,484 - 3,795,973 (+)NCBINCBI36hg18NCBI36
Celera203,889,325 - 3,918,630 (+)NCBI
Cytogenetic Map20p13NCBI
HuRef203,776,247 - 3,805,626 (+)NCBIHuRef
CHM1_1203,827,384 - 3,856,773 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MAVS
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1606258
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.