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Gene: IRGC (immunity related GTPase cinema) Homo sapiens
Symbol: IRGC
Name: immunity related GTPase cinema
Description: Predicted to have GTPase activity. Predicted to be involved in cellular response to interferon-beta and defense response. Predicted to localize to endoplasmic reticulum membrane; INTERACTS WITH aflatoxin B2; benzo[e]pyrene; methapyrilene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CINEMA; IFGGE; Iigp5; immunity-related GTPase cinema 1; immunity-related GTPase family, cinema; immunity-related GTPase family, cinema 1; interferon inducible GTPase 5; interferon-gamma-inducible GTPase IFGGE protein; interferon-inducible GTPase 5; IRGC1; R30953_1
Mus musculus (house mouse) : Irgc1 (immunity-related GTPase family, cinema 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Irgc (immunity related GTPase cinema)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Irgc (immunity related GTPase cinema)
Pan paniscus (bonobo/pygmy chimpanzee) : IRGC (immunity related GTPase cinema)
Canis lupus familiaris (dog) : LOC476445 (interferon-inducible GTPase 5-like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Irgc (immunity related GTPase cinema)
Sus scrofa (pig) : IRGC (immunity related GTPase cinema)
Chlorocebus sabaeus (African green monkey) : IRGC (immunity related GTPase cinema)
Heterocephalus glaber (naked mole-rat) : Irgc (immunity related GTPase cinema)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1943,716,076 - 43,720,021 (+)EnsemblGRCh38hg38GRCh38
GRCh381943,716,068 - 43,720,021 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371944,220,214 - 44,224,173 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361948,912,078 - 48,916,013 (+)NCBINCBI36hg18NCBI36
Celera1941,023,793 - 41,027,752 (+)NCBI
Cytogenetic Map19q13.31NCBI
HuRef1940,652,422 - 40,656,381 (+)NCBIHuRef
CHM1_11944,222,341 - 44,226,300 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on IRGC
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1606259
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.