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Gene: MASP2 (mannan binding lectin serine peptidase 2) Homo sapiens
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Symbol: MASP2
Name: mannan binding lectin serine peptidase 2
Description: Exhibits calcium-dependent protein binding activity; complement component C4b binding activity; and serine-type endopeptidase activity. Involved in complement activation, lectin pathway. Localizes to the extracellular exosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: mannan-binding lectin serine peptidase 1 pseudogene 1; mannan-binding lectin serine peptidase 2; mannan-binding lectin serine protease 1 pseudogene 1; mannan-binding lectin serine protease 2; mannose-binding protein-associated serine protease 2; MAP19; MASP-2; MASP1P1; MBL-associated plasma protein of 19 kD; MBL-associated serine protease 2; small MBL-associated protein; sMAP
Orthologs:
Mus musculus (house mouse) : Masp2 (mannan-binding lectin serine peptidase 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Masp2 (mannan-binding lectin serine peptidase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Masp2 (mannan binding lectin serine peptidase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MASP2 (mannan binding lectin serine peptidase 2)
Canis lupus familiaris (dog) : MASP2 (mannan binding lectin serine peptidase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Masp2 (mannan binding lectin serine peptidase 2)
Sus scrofa (pig) : MASP2 (mannan binding lectin serine peptidase 2)
Chlorocebus sabaeus (green monkey) : MASP2 (mannan binding lectin serine peptidase 2)
Heterocephalus glaber (naked mole-rat) : Masp2 (mannan binding lectin serine peptidase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl111,026,523 - 11,047,239 (-)Ensembl
GRCh38111,026,523 - 11,047,239 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37111,086,580 - 11,107,296 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36111,009,167 - 11,029,872 (-)NCBINCBI36hg18NCBI36
Celera110,198,893 - 10,219,593 (-)NCBI
Cytogenetic Map1p36.22NCBI
HuRef110,238,261 - 10,258,777 (-)NCBIHuRef
CHM1_1111,074,241 - 11,095,206 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on MASP2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1606320
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.