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Gene: PGS1 (phosphatidylglycerophosphate synthase 1) Homo sapiens
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Symbol: PGS1
Name: phosphatidylglycerophosphate synthase 1
Description: Predicted to have CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity and calcium ion binding activity. Predicted to be involved in cardiolipin biosynthetic process and diacylglycerol metabolic process. Localizes to the endoplasmic reticulum; PARTICIPATES IN glycerophospholipid metabolic pathway; cardiolipin biosynthetic pathway; INTERACTS WITH arsane; arsenic atom; cylindrospermopsin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial; DKFZp762M186; MGC131960; PGP synthase 1
Orthologs:
Mus musculus (house mouse) : Pgs1 (phosphatidylglycerophosphate synthase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pgs1 (phosphatidylglycerophosphate synthase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pgs1 (phosphatidylglycerophosphate synthase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PGS1 (phosphatidylglycerophosphate synthase 1)
Canis lupus familiaris (dog) : PGS1 (phosphatidylglycerophosphate synthase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pgs1 (phosphatidylglycerophosphate synthase 1)
Sus scrofa (pig) : PGS1 (phosphatidylglycerophosphate synthase 1)
Chlorocebus sabaeus (green monkey) : PGS1 (phosphatidylglycerophosphate synthase 1)
Heterocephalus glaber (naked mole-rat) : Pgs1 (phosphatidylglycerophosphate synthase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1778,378,649 - 78,425,114 (+)Ensembl
GRCh381778,378,623 - 78,424,659 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371776,374,705 - 76,420,740 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361773,886,330 - 73,932,235 (+)NCBINCBI36hg18NCBI36
Celera1772,968,794 - 73,014,848 (+)NCBI
Cytogenetic Map17q25.3NCBI
HuRef1771,797,363 - 71,843,156 (+)NCBIHuRef
CHM1_11776,438,583 - 76,484,650 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
 
More on PGS1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1606322
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.