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Gene: D2HGDH (D-2-hydroxyglutarate dehydrogenase) Homo sapiens
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Symbol: D2HGDH
Name: D-2-hydroxyglutarate dehydrogenase
Description: Exhibits (R)-2-hydroxyglutarate dehydrogenase activity. Predicted to be involved in several processes, including response to cobalt ion; response to manganese ion; and response to zinc ion. Localizes to the mitochondrion. Implicated in D-2-hydroxyglutaric aciduria 1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D-2-hydroxyglutarate dehydrogenase, mitochondrial; D2HGD; FLJ42195; MGC25181
Orthologs:
Mus musculus (house mouse) : D2hgdh (D-2-hydroxyglutarate dehydrogenase)  MGI  Alliance
Rattus norvegicus (Norway rat) : D2hgdh (D-2-hydroxyglutarate dehydrogenase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : D2hgdh (D-2-hydroxyglutarate dehydrogenase)
Pan paniscus (bonobo/pygmy chimpanzee) : D2HGDH (D-2-hydroxyglutarate dehydrogenase)
Canis lupus familiaris (dog) : D2HGDH (D-2-hydroxyglutarate dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : D2hgdh (D-2-hydroxyglutarate dehydrogenase)
Sus scrofa (pig) : D2HGDH (D-2-hydroxyglutarate dehydrogenase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl2241,734,602 - 241,768,816 (+)Ensembl
GRCh382241,734,629 - 241,768,816 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372242,674,030 - 242,708,231 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362242,322,703 - 242,356,904 (+)NCBINCBI36hg18NCBI36
Celera2236,346,244 - 236,378,542 (+)NCBI
Cytogenetic Map2q37.3NCBI
HuRef2234,429,166 - 234,461,318 (+)NCBIHuRef
CHM1_12242,680,105 - 242,712,785 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on D2HGDH
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1606344
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.