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Gene: PAXX (PAXX non-homologous end joining factor) Homo sapiens
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Symbol: PAXX
Name: PAXX non-homologous end joining factor
Description: Exhibits molecular adaptor activity and protein homodimerization activity. Involved in DNA ligation involved in DNA repair and double-strand break repair via nonhomologous end joining. Localizes to the nonhomologous end joining complex; nucleoplasm; and site of double-strand break. Colocalizes with the Ku70:Ku80 complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C9orf142; chromosome 9 open reading frame 142; hypothetical protein LOC286257; paralog of XRCC4 and XLF; PAXX, non-homologous end joining factor; uncharacterized protein C9orf142; XLS
Orthologs:
Mus musculus (house mouse) : Paxx (non-homologous end joining factor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Paxx (PAXX, non-homologous end joining factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Paxx (PAXX non-homologous end joining factor)
Pan paniscus (bonobo/pygmy chimpanzee) : PAXX (PAXX non-homologous end joining factor)
Canis lupus familiaris (dog) : PAXX (PAXX non-homologous end joining factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Paxx (PAXX non-homologous end joining factor)
Sus scrofa (pig) : PAXX (PAXX non-homologous end joining factor)
Chlorocebus sabaeus (African green monkey) : PAXX (PAXX non-homologous end joining factor)
Heterocephalus glaber (naked mole-rat) : Paxx (PAXX non-homologous end joining factor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl9136,992,422 - 136,993,984 (+)Ensembl
GRCh389136,992,422 - 136,993,976 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379139,886,870 - 139,888,428 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369139,006,691 - 139,008,249 (+)NCBINCBI36hg18NCBI36
Celera9110,399,180 - 110,400,738 (+)NCBI
Cytogenetic Map9q34.3NCBI
HuRef9109,345,976 - 109,347,534 (+)NCBIHuRef
CHM1_19140,035,627 - 140,037,185 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PAXX
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1606404
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.