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Gene: DEFB119 (defensin beta 119) Homo sapiens
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Symbol: DEFB119
Name: defensin beta 119
Description: Exhibits lipopolysaccharide binding activity. Involved in antifungal innate immune response; defense response to Gram-negative bacterium; and defense response to Gram-positive bacterium. Predicted to localize to the extracellular region.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: beta-defensin 119; beta-defensin 120; beta-defensin 19; beta-defensin 20; DEFB-19; DEFB-20; DEFB120; DEFB20; defensin, beta 119; defensin, beta 120; defensin, beta 19; defensin, beta 20; ESC42-RELA; ESC42-RELB; MGC71893
Orthologs:
Mus musculus (house mouse) : Defb19 (defensin beta 19)  MGI  Alliance
Rattus norvegicus (Norway rat) : Defb24 (defensin beta 24)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Defb119 (defensin beta 119)
Pan paniscus (bonobo/pygmy chimpanzee) : DEFB119 (defensin beta 119)
Canis lupus familiaris (dog) : DEFB119 (defensin beta 119)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101955647 (beta-defensin 121)
Sus scrofa (pig) : LOC100157086 (beta-defensin 119)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382031,377,163 - 31,390,649 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372029,964,966 - 29,978,452 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362029,428,628 - 29,442,067 (-)NCBINCBI36hg18NCBI36
Celera2026,721,214 - 26,734,651 (-)NCBI
Cytogenetic Map20q11.21NCBI
HuRef2026,753,722 - 26,767,206 (-)NCBIHuRef
CHM1_12029,868,908 - 29,882,401 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on DEFB119
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1606419
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.