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Gene: AWAT2 (acyl-CoA wax alcohol acyltransferase 2) Homo sapiens
Symbol: AWAT2
Name: acyl-CoA wax alcohol acyltransferase 2
Description: This gene encodes an enzyme belonging to the diacylglycerol acyltransferase family. This enzyme produces wax esters by the esterification of long chain (or wax) alcohols with acyl-CoA-derived fatty acids. It functions in lipid metabolism in the skin, mostly in undifferentiated peripheral sebocytes. This enzyme may also have acyl-CoA:retinol acyltransferase activities, where it catalyzes the synthesis of diacylglycerols and retinyl esters. [provided by RefSeq, May 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: acyl-CoA retinol O-fatty-acyltransferase; ARAT; DC4; DGAT2L4; diacylglycerol O-acyltransferase 2-like protein 4; diacylglycerol O-acyltransferase candidate 4; long-chain-alcohol O-fatty-acyltransferase 2; MFAT; multifunctional O-acyltransferase; retinol O-fatty-acyltransferase; WS
Mus musculus (house mouse) : Awat2 (acyl-CoA wax alcohol acyltransferase 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Awat2 (acyl-CoA wax alcohol acyltransferase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Awat2 (acyl-CoA wax alcohol acyltransferase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : AWAT2 (acyl-CoA wax alcohol acyltransferase 2)
Canis lupus familiaris (dog) : AWAT2 (acyl-CoA wax alcohol acyltransferase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Awat2 (acyl-CoA wax alcohol acyltransferase 2)
Sus scrofa (pig) : AWAT2 (acyl-CoA wax alcohol acyltransferase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X70,040,542 - 70,049,970 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X69,260,392 - 69,269,788 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X69,177,117 - 69,186,513 (-)NCBINCBI36hg18NCBI36
CeleraX69,613,775 - 69,623,166 (-)NCBI
Cytogenetic MapXq13.1NCBI
HuRefX63,081,194 - 63,090,585 (-)NCBIHuRef
CHM1_1X69,154,000 - 69,163,391 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on AWAT2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1606441
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.