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Gene: SH3BP5L (SH3 binding domain protein 5 like) Homo sapiens
Symbol: SH3BP5L
Name: SH3 binding domain protein 5 like
Description: Exhibits Rab guanyl-nucleotide exchange factor activity. Predicted to be involved in intracellular signal transduction and negative regulation of protein tyrosine kinase activity. Predicted to localize to cytoplasm; INTERACTS WITH 17beta-estradiol; 2-methylcholine; aflatoxin B2.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ33845; KIAA1720; SH3 domain-binding protein 5-like; SH3-binding domain protein 5 like; SH3-binding domain protein 5-like; SH3BP-5-like
Mus musculus (house mouse) : Sh3bp5l (SH3 binding domain protein 5 like)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sh3bp5l (SH3 binding domain protein 5 like)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sh3bp5l (SH3 binding domain protein 5 like)
Pan paniscus (bonobo/pygmy chimpanzee) : SH3BP5L (SH3 binding domain protein 5 like)
Canis lupus familiaris (dog) : SH3BP5L (SH3 binding domain protein 5 like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sh3bp5l (SH3 binding domain protein 5 like)
Sus scrofa (pig) : SH3BP5L (SH3 binding domain protein 5 like)
Chlorocebus sabaeus (African green monkey) : SH3BP5L (SH3 binding domain protein 5 like)
Heterocephalus glaber (naked mole-rat) : Sh3bp5l (SH3 binding domain protein 5 like)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1248,810,446 - 248,825,915 (-)EnsemblGRCh38hg38GRCh38
GRCh381248,810,446 - 248,825,915 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371249,104,645 - 249,120,154 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361247,071,274 - 247,086,777 (-)NCBINCBI36hg18NCBI36
Celera1222,266,041 - 222,281,391 (-)NCBI
Cytogenetic Map1q44NCBI
HuRef1219,345,673 - 219,361,176 (-)NCBIHuRef
CHM1_11250,376,942 - 250,392,777 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SH3BP5L
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1606500
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.