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Gene: PPEF1 (protein phosphatase with EF-hand domain 1) Homo sapiens
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Symbol: PPEF1
Name: protein phosphatase with EF-hand domain 1
Description: This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein has been suggested to play a role in specific sensory neuron function and/or development. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene. Several alternatively spliced transcript variants, each encoding a distinct isoform, have been described. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: PP7; PPEF; PPP7C; PPP7CA; protein phosphatase 7, catalytic subunit, alpha isozyme; protein phosphatase with EF calcium-binding domain; protein phosphatase, serine/threonine type, with EF-hands; serine/threonine protein phosphatase 7; serine/threonine-protein phosphatase 7; serine/threonine-protein phosphatase with EF-hands 1
Orthologs:
Mus musculus (house mouse) : Ppef1 (protein phosphatase with EF hand calcium-binding domain 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ppef1 (protein phosphatase with EF-hand domain 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppef1 (protein phosphatase with EF-hand domain 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PPEF1 (protein phosphatase with EF-hand domain 1)
Canis lupus familiaris (dog) : PPEF1 (protein phosphatase with EF-hand domain 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppef1 (protein phosphatase with EF-hand domain 1)
Sus scrofa (pig) : PPEF1 (protein phosphatase with EF-hand domain 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X18,675,909 - 18,827,921 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X18,704,257 - 18,846,039 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X18,618,966 - 18,755,956 (+)NCBINCBI36hg18NCBI36
CeleraX22,829,137 - 22,966,124 (+)NCBI
Cytogenetic MapXp22.13NCBI
HuRefX16,462,688 - 16,598,790 (+)NCBIHuRef
CHM1_1X18,740,148 - 18,877,076 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PPEF1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1606579
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.