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Gene: PYHIN1 (pyrin and HIN domain family member 1) Homo sapiens
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Symbol: PYHIN1
Name: pyrin and HIN domain family member 1
Description: Exhibits ubiquitin protein ligase binding activity. Involved in several processes, including cellular response to interferon-alpha; positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; and positive regulation of nitrogen compound metabolic process. Localizes to protein-containing complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: IFIX; interferon-inducible protein X; MGC23885; pyrin and HIN domain family, member 1; pyrin and HIN domain-containing protein 1; RP11-520H16.1
Orthologs:
Pan paniscus (bonobo/pygmy chimpanzee) : PYHIN1 (pyrin and HIN domain family member 1)
Chlorocebus sabaeus (African green monkey) : PYHIN1 (pyrin and HIN domain family member 1)
more info ...
Related Pseudogenes: PYHIN5P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1158,930,796 - 158,977,059 (+)EnsemblGRCh38hg38GRCh38
GRCh381158,931,547 - 158,990,909 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371158,901,337 - 158,946,849 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361157,167,966 - 157,213,468 (+)NCBINCBI36hg18NCBI36
Celera1131,971,636 - 132,017,127 (+)NCBI
Cytogenetic Map1q23.1NCBI
HuRef1130,258,714 - 130,304,150 (+)NCBIHuRef
CHM1_11160,295,392 - 160,340,938 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PYHIN1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1606702
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.