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Gene: ITIH5 (inter-alpha-trypsin inhibitor heavy chain 5) Homo sapiens
Symbol: ITIH5
Name: inter-alpha-trypsin inhibitor heavy chain 5
CRRD ID: 1606774
Description: Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in hyaluronan metabolic process and negative regulation of endopeptidase activity. Localizes to collagen-containing extracellular matrix.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp686F0145; inter-alpha (globulin) inhibitor H5; inter-alpha trypsin inhibitor heavy chain precursor 5; inter-alpha-inhibitor heavy chain 5; inter-alpha-trypsin inhibitor heavy chain family member 5; inter-alpha-trypsin inhibitor heavy chain family, member 5; inter-alpha-trypsin inhibitor heavy chain H5; ITI heavy chain H5; ITI-HC5; MGC10848; PP14776
Mus musculus (house mouse) : Itih5 (inter-alpha (globulin) inhibitor H5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itih5 (inter-alpha-trypsin inhibitor heavy chain 5)
Pan paniscus (bonobo/pygmy chimpanzee) : ITIH5 (inter-alpha-trypsin inhibitor heavy chain 5)
Canis lupus familiaris (dog) : ITIH5 (inter-alpha-trypsin inhibitor heavy chain 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itih5 (inter-alpha-trypsin inhibitor heavy chain 5)
Sus scrofa (pig) : ITIH5 (inter-alpha-trypsin inhibitor heavy chain 5)
Chlorocebus sabaeus (African green monkey) : ITIH5 (inter-alpha-trypsin inhibitor heavy chain 5)
Heterocephalus glaber (naked mole-rat) : Itih5 (inter-alpha-trypsin inhibitor heavy chain 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl107,559,270 - 7,666,998 (-)EnsemblGRCh38hg38GRCh38
GRCh38107,559,270 - 7,666,968 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37107,601,232 - 7,708,961 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36107,641,641 - 7,748,940 (-)NCBINCBI36hg18NCBI36
Celera107,527,158 - 7,634,731 (-)NCBI
Cytogenetic Map10p14NCBI
HuRef107,519,930 - 7,627,275 (-)NCBIHuRef
CHM1_1107,602,252 - 7,709,490 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ITIH5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1606774
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.