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Gene: BMT2 (base methyltransferase of 25S rRNA 2 homolog) Homo sapiens
Symbol: BMT2
Name: base methyltransferase of 25S rRNA 2 homolog
Description: Exhibits S-adenosyl-L-methionine binding activity. Involved in cellular response to amino acid starvation and negative regulation of TORC1 signaling. Colocalizes with the GATOR1 complex and KICSTOR complex; INTERACTS WITH 2-hydroxypropanoic acid; aflatoxin B1; aflatoxin M1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C7orf60; chromosome 7 open reading frame 60; FLJ31818; hypothetical protein LOC154743; probable methyltransferase BMT2 homolog; probable methyltransferase BTM2 homolog; S-adenosylmethionine sensor upstream of mTORC1; SAMTOR; UPF0532 protein C7orf60
Mus musculus (house mouse) : Bmt2 (base methyltransferase of 25S rRNA 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Bmt2 (base methyltransferase of 25S rRNA 2 homolog)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bmt2 (base methyltransferase of 25S rRNA 2 homolog)
Pan paniscus (bonobo/pygmy chimpanzee) : BMT2 (base methyltransferase of 25S rRNA 2 homolog)
Canis lupus familiaris (dog) : BMT2 (base methyltransferase of 25S rRNA 2 homolog)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bmt2 (base methyltransferase of 25S rRNA 2 homolog)
Sus scrofa (pig) : BMT2 (base methyltransferase of 25S rRNA 2 homolog)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh387112,819,147 - 112,939,875 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377112,459,202 - 112,579,932 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367112,246,438 - 112,367,168 (-)NCBINCBI36hg18NCBI36
Celera7107,271,822 - 107,392,595 (-)NCBI
Cytogenetic Map7q31.1NCBI
HuRef7106,827,013 - 106,948,026 (-)NCBIHuRef
CHM1_17112,392,867 - 112,513,647 (-)NCBICHM1_1
CRA_TCAGchr7v27111,827,660 - 111,948,430 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on BMT2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1606951
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.