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Gene: BMT2 (base methyltransferase of 25S rRNA 2 homolog) Homo sapiens
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Symbol: BMT2
Name: base methyltransferase of 25S rRNA 2 homolog
Description: Exhibits S-adenosyl-L-methionine binding activity. Involved in cellular response to amino acid starvation and negative regulation of TORC1 signaling. Colocalizes with the GATOR1 complex and KICSTOR complex; INTERACTS WITH 2-hydroxypropanoic acid; aflatoxin B1; aflatoxin M1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C7orf60; chromosome 7 open reading frame 60; FLJ31818; hypothetical protein LOC154743; probable methyltransferase BMT2 homolog; probable methyltransferase BTM2 homolog; S-adenosylmethionine sensor upstream of mTORC1; SAMTOR; UPF0532 protein C7orf60
Orthologs:
Mus musculus (house mouse) : Bmt2 (base methyltransferase of 25S rRNA 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Bmt2 (base methyltransferase of 25S rRNA 2 homolog)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bmt2 (base methyltransferase of 25S rRNA 2 homolog)
Pan paniscus (bonobo/pygmy chimpanzee) : BMT2 (base methyltransferase of 25S rRNA 2 homolog)
Canis lupus familiaris (dog) : BMT2 (base methyltransferase of 25S rRNA 2 homolog)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bmt2 (base methyltransferase of 25S rRNA 2 homolog)
Sus scrofa (pig) : BMT2 (base methyltransferase of 25S rRNA 2 homolog)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387112,819,147 - 112,939,875 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377112,459,202 - 112,579,932 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367112,246,438 - 112,367,168 (-)NCBINCBI36hg18NCBI36
Celera7107,271,822 - 107,392,595 (-)NCBI
Cytogenetic Map7q31.1NCBI
HuRef7106,827,013 - 106,948,026 (-)NCBIHuRef
CHM1_17112,392,867 - 112,513,647 (-)NCBICHM1_1
CRA_TCAGchr7v27111,827,660 - 111,948,430 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on BMT2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1606951
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.