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Gene: SRSF12 (serine and arginine rich splicing factor 12) Homo sapiens
Symbol: SRSF12
Name: serine and arginine rich splicing factor 12
Description: Exhibits RNA binding activity. Involved in mRNA 5'-splice site recognition and regulation of alternative mRNA splicing, via spliceosome. Predicted to localize to cytoplasm and nuclear speck; PARTICIPATES IN spliceosome pathway; INTERACTS WITH 4,4'-sulfonyldiphenol; aflatoxin B1; cisplatin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 35 kDa SR repressor protein; FLJ14459; FLJ33484; FLJ41221; RP11-63L7.3; serine-arginine repressor protein (35 kDa); serine/arginine-rich splicing factor 12; SFRS13B; SFRS19; splicing factor, arginine/serine-rich 13B; splicing factor, arginine/serine-rich 19; SR splicing factor 12; SRrp35
Mus musculus (house mouse) : Srsf12 (serine and arginine-rich splicing factor 12)  MGI  Alliance
Rattus norvegicus (Norway rat) : Srsf12 (serine and arginine rich splicing factor 12)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Srsf12 (serine and arginine rich splicing factor 12)
Pan paniscus (bonobo/pygmy chimpanzee) : SRSF12 (serine and arginine rich splicing factor 12)
Canis lupus familiaris (dog) : SRSF12 (serine and arginine rich splicing factor 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Srsf12 (serine and arginine rich splicing factor 12)
Sus scrofa (pig) : SRSF12 (serine and arginine rich splicing factor 12)
Chlorocebus sabaeus (African green monkey) : SRSF12 (serine and arginine rich splicing factor 12)
Heterocephalus glaber (naked mole-rat) : Srsf12 (serine and arginine rich splicing factor 12)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl689,095,959 - 89,118,071 (-)EnsemblGRCh38hg38GRCh38
GRCh38689,095,957 - 89,118,071 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37689,805,678 - 89,827,800 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36689,862,397 - 89,884,519 (-)NCBINCBI36hg18NCBI36
Celera690,223,565 - 90,245,681 (-)NCBI
Cytogenetic Map6q15NCBI
HuRef687,021,299 - 87,043,399 (-)NCBIHuRef
CHM1_1689,903,664 - 89,925,768 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SRSF12
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1606967
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2020-07-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.