Olfr1466 (olfactory receptor 1466) - Chinchilla Research Resource Database

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Gene: Olfr1466 (olfactory receptor 1466) Mus musculus

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General
Array IDs
References

Symbol:

Olfr1466

Name:

olfactory receptor 1466

Description:

Predicted to have odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to localize to the integral component of membrane. Orthologous to human OR5B3 (olfactory receptor family 5 subfamily B member 3).

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

GA_x6K02T2RE5P-3672907-3673839; MOR202-12; olfactory receptor MOR202-12

Orthologs:

No known orthologs.

homologs ...

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Other homologs ²				less info ...
Homo sapiens (human):	OR5B3 (olfactory receptor family 5 subfamily B member 3)	HGNC	Ensembl, OrthoDB, Panther, PhylomeDB, Treefam
Homo sapiens (human):	OR5B17 (olfactory receptor family 5 subfamily B member 17)	HGNC	OrthoDB, Panther
Homo sapiens (human):	OR5B2 (olfactory receptor family 5 subfamily B member 2)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	OR5B3 (olfactory receptor family 5 subfamily B member 3)	Alliance	DIOPT (Ensembl Compara, PANTHER, PhylomeDB, TreeFam)

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm38	19	13,341,760 - 13,344,328 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
MGSCv37	19	13,416,250 - 13,417,182 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	19	13,408,779 - 13,409,711 (+)	NCBI			mm8
Celera	19	14,011,489 - 14,012,421 (+)	NCBI		Celera
Cytogenetic Map	19	A	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation (Toggle Annotation Detail/Summary View)

Gene-Chemical Interaction Annotations

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
acrylamide	increases expression	EXP		6480464	Acrylamide results in increased expression of OLFR1466 mRNA	CTD	PMID:30807115
carbon nanotube	decreases expression	EXP		6480464	Nanotubes, Carbon analog results in decreased expression of OLFR1466 mRNA	CTD	PMID:25554681
dextran sulfate	multiple interactions	EXP		6480464	[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OLFR1466 mRNA	CTD	PMID:29950665
titanium dioxide	multiple interactions	EXP		6480464	[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OLFR1466 mRNA	CTD	PMID:29950665
valproic acid	affects expression	EXP		6480464	Valproic Acid affects the expression of OLFR1466 mRNA	CTD	PMID:17963808

Gene Ontology Annotations

Biological Process

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
G protein-coupled receptor signaling pathway		ISA	protein_id:AAC52910	2290270	(MGI:MGI:3029684, PMID:14611657)	MGI	MGI:MGI:3029684, PMID:14611657
G protein-coupled receptor signaling pathway		IBA	MGI:MGI:2151908 more ...	2290270	(PMID:21873635)	GO_Central	PMID:21873635
sensory perception of smell		ISA	protein_id:AAC52910	2290270	(MGI:MGI:3029684, PMID:14611657)	MGI	MGI:MGI:3029684, PMID:14611657
sensory perception of smell		IBA	MGI:MGI:2151908 more ...	2290270	(PMID:21873635)	GO_Central	PMID:21873635

Cellular Component

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
integral component of membrane		ISA	protein_id:AAC52910	2290270	(MGI:MGI:3029684, PMID:14611657)	MGI	MGI:MGI:3029684, PMID:14611657

Molecular Function

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
odorant binding		IBA	MGI:MGI:2151908 more ...	2290270	(PMID:21873635)	GO_Central	PMID:21873635
olfactory receptor activity		ISA	protein_id:AAC52910	2290270	(MGI:MGI:3029684, PMID:14611657)	MGI	MGI:MGI:3029684, PMID:14611657
olfactory receptor activity		IBA	MGI:MGI:2151908 more ...	2290270	(PMID:21873635)	GO_Central	PMID:21873635

Gene-Chemical Interaction Annotations

	acrylamide (EXP)
	carbon nanotube (EXP)

	dextran sulfate (EXP)
	titanium dioxide (EXP)

valproic acid (EXP)

Gene Ontology Annotations

Biological Process

	G protein-coupled receptor signaling pathway (IBA,ISA)
	sensory perception of smell (IBA,ISA)

Cellular Component

integral component of membrane (ISA)

Molecular Function

odorant binding (IBA)

olfactory receptor activity (IBA,ISA)

References - curated

1.	RGD automated import pipeline for gene-chemical interactions

References - uncurated

PubMed

11802173 11875048 14611657 21873635

Genomics

Position Markers

UniSTS:489411

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	19	13,341,760 - 13,342,692	UniSTS	GRCm38
MGSCv37	19	13,416,250 - 13,417,182	UniSTS	GRCm37
Celera	19	14,011,489 - 14,012,421	UniSTS
Cytogenetic Map	19	C1	UniSTS

UniSTS:495626

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	19	13,341,725 - 13,342,771	UniSTS	GRCm38
MGSCv37	19	13,416,215 - 13,417,261	UniSTS	GRCm37
Celera	19	14,011,454 - 14,012,500	UniSTS
Cytogenetic Map	19	C1	UniSTS

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

CRRD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300776	Lfp3_m	long free running period 3 (mouse)			Not determined		19	1	20278703	Mouse
4142161	Drinksac2_m	drink saccharin 2 (mouse)			Not determined			1	20645286	Mouse
4142302	Nstr1_m	nerve sheath tumor resistance QTL 1 (mouse)			Not determined		19	1	22321310	Mouse
1301271	Datd_m	dopamine transporter density (mouse)			Not determined		19	1	32362870	Mouse
4142406	Pbctlp1_m	peripheral blood cytotoxic T lymphocyte percentage 1 (mouse)			Not determined			1	32897810	Mouse
1300904	Chab5_m	cholesterol absorption 5 (mouse)			Not determined		19	1676400	35676563	Mouse
1357819	Tgct2_m	testicular germ cell tumor 2 (mouse)			Not determined		19	3278551	20562299	Mouse
1300923	Bits4_m	bitterness sensitivity 4 (mouse)			Not determined		19	3345852	37345984	Mouse
1301800	Faq10_m	fluctuating asymmetry QTL 10 (mouse)			Not determined		19	3345852	37345984	Mouse
1300591	Pas3_m	pulmonary adenoma susceptibility 3 (mouse)			Not determined		19	3345852	37345984	Mouse
1302126	Skull26_m	skull morphology 26 (mouse)			Not determined		19	3345852	37345984	Mouse
11039522	Tbbr4_m	Trypanosoma brucei brucei response 4 (mouse)					19	5335962	39336106	Mouse
1301228	Iba4_m	induction of brown adipocytes 4 (mouse)			Not determined		19	9328315	43328421	Mouse
1302019	Pgia23_m	proteoglycan induced arthritis 23 (mouse)			Not determined		19	9810053	43810202	Mouse
14928311	Manh85_m	mandible shape 85 (mouse)					19	11937389	45937389	Mouse

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	7
Count of miRNA genes:	7
Interacting mature miRNAs:	7
Transcripts:	ENSMUST00000075868
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences

RefSeq Transcripts	NM_146694	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_030250947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_030250948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC131758	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY073401	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY318685	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466534	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

NM_146694 ⟹ NP_666905

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	19	13,341,760 - 13,342,692 (+)	NCBI
MGSCv37	19	13,416,250 - 13,417,182 (+)	RGD
Celera	19	14,011,489 - 14,012,421 (+)	RGD
cM Map	19		ENTREZGENE

Sequence:

show sequence

ATGACATCATTGAACAACTTGACAGAAGTGACACACTTTCTCCTGCTGGGACTCACTGATGATC
CAGGCCTGCAACTTCCCCTTTTCATCATTTTTCTTCTCATCTACATCATTACCCTGGTAGGGAA
CCTGGGGATGATCCTGTTGATTCTCTTGGACTCTCGGCTCCATATCCCCATGTACTTTTTCCTT
GCTAACTTGTCCCTGGTGGATGTTATTTACTCTTCAGCGGTCACACCAAAAGTCATGGCTGGTC
TCATAATAGGAGATAATCTCATTTCTTACAATGAGTGTGCAGCTCAGATGTTCTTTTTTGCAGC
CTTTGCTACTGTTGAAAATTATCTGTTGACTTCAATGGCCTGTGATCGCTATGCAGCAGTGTGT
AAACCCCTATACTATGCTACCACCATGACTCCAAGTGTATGTATGTGTTTCATCATGGGCTGCT
ATGCTCTTGGGTTCTTAAATGCCTCAGTTTATCTTGGAAATACATTCAGTCTTTCTTTCTGTAA
ATCTAATGTGGTTCATCATTTTTTCTGTGATATGCCAGCAATCATGGCTCTCTCTTGCTCTGAT
AGACATGTTAATGAACTGGTACTTATTTATCAAGCCAGTTTTATTATCTTCTTTGCTCTCATAA
TAATATTAATATCATATATTATAATTTTTATCACAATCTTAAAGATGCACTCAGAAGCAGGAGT
TCAGAAGGCTCTTTCCACTTGTGCTTCCCACTTTACTGCTGTTTTTATTTTCTATGGAACAACA
ATCTTCATGTATTTGCAGCCAAGCTCTAGACATGCAATGGACACGGACAAAATTGTGTCTGTCT
TCTACACCATGGTCATTCCCATGCTGAACCCTTTAGTTTACAGCCTGAGAAATAAAGAAGTAAA
GAGTGCATTCATGAAAGTAGTTTTGAAAGAAAAATAA

hide sequence

RefSeq Acc Id:

XM_030250947 ⟹ XP_030106807

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	19	13,341,760 - 13,344,328 (+)	NCBI

RefSeq Acc Id:

XM_030250948 ⟹ XP_030106808

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	19	13,341,760 - 13,342,785 (+)	NCBI

Protein Sequences

Protein RefSeqs	NP_666905	(Get FASTA)	NCBI Sequence Viewer
	XP_030106807	(Get FASTA)	NCBI Sequence Viewer
	XP_030106808	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAL61064	(Get FASTA)	NCBI Sequence Viewer
	AAP71830	(Get FASTA)	NCBI Sequence Viewer
	EDL41503	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_666905 ⟸ NM_146694

- UniProtKB:

Q8VFW4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTSLNNLTEVTHFLLLGLTDDPGLQLPLFIIFLLIYIITLVGNLGMILLILLDSRLHIPMYFFL
ANLSLVDVIYSSAVTPKVMAGLIIGDNLISYNECAAQMFFFAAFATVENYLLTSMACDRYAAVC
KPLYYATTMTPSVCMCFIMGCYALGFLNASVYLGNTFSLSFCKSNVVHHFFCDMPAIMALSCSD
RHVNELVLIYQASFIIFFALIIILISYIIIFITILKMHSEAGVQKALSTCASHFTAVFIFYGTT
IFMYLQPSSRHAMDTDKIVSVFYTMVIPMLNPLVYSLRNKEVKSAFMKVVLKEK

hide sequence

RefSeq Acc Id:	XP_030106807 ⟸ XM_030250947
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_030106808 ⟸ XM_030250948
- Peptide Label:	isoform X2

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:3031300	AgrOrtholog
Ensembl Genes	ENSMUSG00000096485	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000075265	ENTREZGENE, UniProtKB/TrEMBL
	ENSMUSP00000147188	UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000075868	ENTREZGENE, UniProtKB/TrEMBL
	ENSMUST00000207124	UniProtKB/TrEMBL
InterPro	7TM_GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_supfam	UniProtKB/TrEMBL
	Olfact_rcpt	UniProtKB/TrEMBL
KEGG Report	mmu:258689	UniProtKB/TrEMBL
MGD	MGI:3031300	ENTREZGENE
NCBI Gene	258689	ENTREZGENE
Pfam	7tm_4	UniProtKB/TrEMBL
PhenoGen	Olfr1466	PhenoGen
PRINTS	GPCRRHODOPSN	UniProtKB/TrEMBL
	OLFACTORYR	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
UniGene	Mm.271530	ENTREZGENE
UniProt	Q8VFW4	ENTREZGENE, UniProtKB/TrEMBL

More on Olfr1466
	Alliance Gene
	NCBI Gene
	Ensembl Gene
	JBrowse: mm9 mm10
	MGI Report
	NCBI Genome Data Viewer

CRRD Object Information
CRRD ID:	1614097
Created:	2007-04-30
Species:	Mus musculus
Last Modified:	2019-11-27
Status:	ACTIVE

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.