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Gene: Brk1 (BRICK1, SCAR/WAVE actin-nucleating complex subunit) Mus musculus
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Symbol: Brk1
Name: BRICK1, SCAR/WAVE actin-nucleating complex subunit
Description: Predicted to contribute to Rac GTPase binding activity. Involved in several processes, including actin cytoskeleton organization; in utero embryonic development; and positive regulation of cell population proliferation. Localizes to the lamellipodium. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system gland; lung; and nervous system. Orthologous to human BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex); PARTICIPATES IN platelet-derived growth factor signaling pathway; INTERACTS WITH 2,3',4,4',5-Pentachlorobiphenyl; clobetasol; ethanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 6720456B07Rik; AW011779; probable protein BRICK1; protein BRICK1
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl6113,604,772 - 113,616,951 (+)Ensembl
GRCm386113,604,772 - 113,616,951 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376113,554,766 - 113,566,945 (+)NCBIGRCm37mm9NCBIm37
MGSCv366113,570,549 - 113,582,728 (+)NCBImm8
Celera6115,431,613 - 115,443,812 (+)NCBICelera
Cytogenetic Map6 E3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Brk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1614238
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.