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Gene: Serpina1e (serine (or cysteine) peptidase inhibitor, clade A, member 1E) Mus musculus
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Symbol: Serpina1e
Name: serine (or cysteine) peptidase inhibitor, clade A, member 1E
Description: Predicted to have identical protein binding activity; protease binding activity; and serine-type endopeptidase inhibitor activity. Involved in response to cytokine and response to peptide hormone. Predicted to localize to the Golgi apparatus; endoplasmic reticulum; and extracellular space. Human ortholog(s) of this gene implicated in several diseases, including alpha 1-antitrypsin deficiency; artery disease (multiple); chronic obstructive pulmonary disease (multiple); inflammatory bowel disease (multiple); and liver disease (multiple). Is expressed in gut; liver lobe; metanephros; and nucleus pulposus. Orthologous to human SERPINA1 (serpin family A member 1); PARTICIPATES IN coagulation cascade pathway; complement system pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-1 protease inhibitor 5; alpha-1-antitrypsin 1-5; Dom5; PI5; serine (or cysteine) proteinase inhibitor, clade A, member 1e; serine protease inhibitor 1-5; serine protease inhibitor A1e; serpin A1e; Spi1-5
Orthologs:
No known orthologs. homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl12103,946,931 - 103,958,975 (-)Ensembl
GRCm3812103,946,931 - 103,956,897 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712105,185,141 - 105,195,107 (-)NCBIGRCm37mm9NCBIm37
MGSCv3612104,347,981 - 104,357,947 (-)NCBImm8
Celera12105,163,634 - 105,173,624 (-)NCBICelera
Cytogenetic Map12 ENCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Serpina1e
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1614435
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.