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Gene: Serpina1d (serine (or cysteine) peptidase inhibitor, clade A, member 1D) Mus musculus
Symbol: Serpina1d
Name: serine (or cysteine) peptidase inhibitor, clade A, member 1D
Description: Predicted to have identical protein binding activity; protease binding activity; and serine-type endopeptidase inhibitor activity. Involved in response to cytokine and response to peptide hormone. Localizes to the extracellular region. Human ortholog(s) of this gene implicated in several diseases, including alpha 1-antitrypsin deficiency; artery disease (multiple); chronic obstructive pulmonary disease (multiple); inflammatory bowel disease (multiple); and liver disease (multiple). Is expressed in gut and liver lobe. Orthologous to human SERPINA1 (serpin family A member 1); PARTICIPATES IN coagulation cascade pathway; complement system pathway; INTERACTS WITH 4,4'-sulfonyldiphenol; benzo[a]pyrene; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AAT; AI118301; Alpha-1 protease inhibitor 1; alpha-1 protease inhibitor 4; Alpha-1-antiproteinase; Alpha-1-antitrypsin 1-1; alpha-1-antitrypsin 1-4; DOM-7; Dom1; Dom4; expressed sequence AI118301; PI4; serine (or cysteine) proteinase inhibitor, clade A, member 1d; Serine protease inhibitor 1-1; serine protease inhibitor 1-4; Serine protease inhibitor A1a; serine protease inhibitor A1d; Serpin A1a; serpin A1d; Serpina1 DOM-7; Serpina1a; Spi1-1; Spi1-4
No known orthologs. homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl12103,763,594 - 103,773,592 (-)Ensembl
GRCm3812103,763,587 - 103,773,633 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712105,001,797 - 105,011,843 (-)NCBIGRCm37mm9NCBIm37
MGSCv3612104,164,644 - 104,174,683 (-)NCBImm8
Celera1289,308,089 - 89,318,471 (-)NCBICelera
Cytogenetic Map12 ENCBI
cM Map1252.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Serpina1d
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1614436
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.