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Gene: Mavs (mitochondrial antiviral signaling protein) Mus musculus
Symbol: Mavs
Name: mitochondrial antiviral signaling protein
Description: Exhibits signaling adaptor activity. Involved in several processes, including positive regulation of cytokine production; positive regulation of defense response to virus by host; and regulation of peroxisome organization. Localizes to the mitochondrion and peroxisome. Orthologous to human MAVS (mitochondrial antiviral signaling protein); PARTICIPATES IN hepatitis C pathway; influenza A pathway; measles pathway; INTERACTS WITH 5-aza-2'-deoxycytidine; aflatoxin B1; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CARD adapter inducing interferon beta; CARD adapter inducing interferon-beta; cardif; D430028G21Rik; IFN-beta promoter stimulator-1; interferon beta promoter stimulator protein 1; interferon-beta promoter stimulator protein 1; IPS-1; MGC25836; mitochondrial anti-viral signaling protein; mitochondrial antiviral-signaling protein; RP23-387C21.3; virus-induced signaling adapter; virus-induced-signaling adapter; Visa
Homo sapiens (human) : MAVS (mitochondrial antiviral signaling protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mavs (mitochondrial antiviral signaling protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mavs (mitochondrial antiviral signaling protein)
Pan paniscus (bonobo/pygmy chimpanzee) : MAVS (mitochondrial antiviral signaling protein)
Canis lupus familiaris (dog) : MAVS (mitochondrial antiviral signaling protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mavs (mitochondrial antiviral signaling protein)
Sus scrofa (pig) : MAVS (mitochondrial antiviral signaling protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm382131,234,063 - 131,248,025 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372131,059,874 - 131,073,761 (+)NCBIGRCm37mm9NCBIm37
MGSCv362130,925,579 - 130,939,466 (+)NCBImm8
Celera2132,460,419 - 132,474,382 (+)NCBICelera
Cytogenetic Map2 F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Mavs
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1614930
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.