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Gene: Tnfaip3 (tumor necrosis factor, alpha-induced protein 3) Mus musculus
Symbol: Tnfaip3
Name: tumor necrosis factor, alpha-induced protein 3
CRRD ID: 1615155
Description: Exhibits kinase binding activity. Involved in several processes, including negative regulation of cytokine production; negative regulation of defense response; and negative regulation of signal transduction. Localizes to cytoplasm. Is expressed in central nervous system; genitourinary system; heart; and retina nuclear layer. Orthologous to human TNFAIP3 (TNF alpha induced protein 3); PARTICIPATES IN nuclear factor kappa B signaling pathway; tumor necrosis factor mediated signaling pathway; measles pathway; INTERACTS WITH (S)-amphetamine; 1,1-dichloroethene; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A2; A20; putative DNA-binding protein A20; Tnf; TNF alpha-induced protein 3; Tnfip3; tumor necrosis factor alpha-induced protein 3; tumor necrosis factor induced protein 3; zinc finger protein A20
Homo sapiens (human) : TNFAIP3 (TNF alpha induced protein 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tnfaip3 (TNF alpha induced protein 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnfaip3 (TNF alpha induced protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TNFAIP3 (TNF alpha induced protein 3)
Canis lupus familiaris (dog) : TNFAIP3 (TNF alpha induced protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnfaip3 (TNF alpha induced protein 3)
Sus scrofa (pig) : TNFAIP3 (TNF alpha induced protein 3)
Chlorocebus sabaeus (African green monkey) : TNFAIP3 (TNF alpha induced protein 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391018,876,658 - 18,891,158 (-)NCBI
GRCm381019,000,910 - 19,015,410 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1019,000,910 - 19,015,657 (-)EnsemblGRCm38mm10GRCm38
MGSCv371018,720,716 - 18,735,216 (-)NCBIGRCm37mm9NCBIm37
MGSCv361018,690,332 - 18,704,783 (-)NCBImm8
Celera1018,907,568 - 18,922,063 (-)NCBICelera
Cytogenetic Map10A3NCBI
cM Map108.08NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tnfaip3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1615155
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-10-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.