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Gene: Tnc (tenascin C) Mus musculus
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Symbol: Tnc
Name: tenascin C
Description: Predicted to have fibronectin binding activity and syndecan binding activity. Involved in several processes, including neuromuscular junction development; peripheral nervous system axon regeneration; and prostate gland development. Localizes to the basement membrane; interstitial matrix; and perisynaptic extracellular matrix. Human ortholog(s) of this gene implicated in allergic conjunctivitis; asthma; autosomal dominant nonsyndromic deafness 56; and pulmonary hypertension. Is expressed in several structures, including alimentary system; brain; ovary; sensory organ; and skeleton. Orthologous to human TNC (tenascin C); PARTICIPATES IN cell-extracellular matrix signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid; 2,6-di-tert-butyl-4-methylphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI528729; C130033P17Rik; cytotactin; hexabrachion; Hxb; MGC144208; MGC144209; Ten; tenascin; tenascin-C; TN; TN-C
Orthologs:
Homo sapiens (human) : TNC (tenascin C)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tnc (tenascin C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnc (tenascin C)
Pan paniscus (bonobo/pygmy chimpanzee) : TNC (tenascin C)
Canis lupus familiaris (dog) : TNC (tenascin C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnc (tenascin C)
Sus scrofa (pig) : TNC (tenascin C)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38463,959,785 - 64,047,015 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37463,620,819 - 63,681,760 (-)NCBIGRCm37mm9NCBIm37
MGSCv36463,446,149 - 63,507,087 (-)NCBImm8
Celera462,620,454 - 62,707,711 (-)NCBICelera
Cytogenetic Map4 C1NCBI
cM Map434.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tnc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1615156
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.