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Gene: Sorl1 (sortilin-related receptor, LDLR class A repeats-containing) Mus musculus
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Symbol: Sorl1
Name: sortilin-related receptor, LDLR class A repeats-containing
Description: Predicted to have ADP-ribosylation factor binding activity; amyloid-beta binding activity; and low-density lipoprotein particle binding activity. Involved in several processes, including diet induced thermogenesis; negative regulation of protein metabolic process; and regulation of signal transduction. Localizes to the nuclear envelope lumen. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is expressed in several structures, including alimentary system; brain; ganglia; metanephros; and sensory organ. Orthologous to human SORL1 (sortilin related receptor 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2900010L19Rik; AI596264; AW261561; gp250; LDLR relative with 11 ligand-binding repeats; low-density lipoprotein receptor relative with 11 ligand-binding repeats; LR11; mSorLA; SorLA; sorLA-1; sortilin-related receptor; sorting protein-related receptor containing LDLR class A repeats
Orthologs:
Homo sapiens (human) : SORL1 (sortilin related receptor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sorl1 (sortilin related receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sorl1 (sortilin related receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SORL1 (sortilin related receptor 1)
Canis lupus familiaris (dog) : SORL1 (sortilin related receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sorl1 (sortilin related receptor 1)
Sus scrofa (pig) : SORL1 (sortilin related receptor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38941,964,709 - 42,124,297 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37941,776,572 - 41,932,372 (-)NCBIGRCm37mm9NCBIm37
MGSCv36941,719,598 - 41,875,108 (-)NCBImm8
Celera939,209,765 - 39,348,584 (-)NCBICelera
Cytogenetic Map9 A5.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sorl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1615161
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.