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Gene: Adh5 (alcohol dehydrogenase 5 (class III), chi polypeptide) Mus musculus
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Symbol: Adh5
Name: alcohol dehydrogenase 5 (class III), chi polypeptide
Description: Exhibits S-(hydroxymethyl)glutathione dehydrogenase activity; alcohol dehydrogenase (NAD+) activity; and identical protein binding activity. Involved in several processes, including formaldehyde catabolic process; peptidyl-cysteine S-nitrosylation; and response to lipopolysaccharide. Localizes to mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and respiratory system. Human ortholog(s) of this gene implicated in asthma. Orthologous to human ADH5 (alcohol dehydrogenase 5 (class III), chi polypeptide); PARTICIPATES IN gluconeogenesis pathway; glycolysis pathway; glycolysis/gluconeogenesis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Adh-5; ADH-B2; Adh3; alcohol dehydrogenase 2; alcohol dehydrogenase B2; alcohol dehydrogenase class-3; alcohol dehydrogenase class-III; FALDH; FDH; glutathione-dependent formaldehyde dehydrogenase; GSH-FDH; GSNOR; S-(hydroxymethyl)glutathione dehydrogenase; S-nitrosoglutathione reductase
Orthologs:
Related Pseudogenes: Adh5-ps1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl3138,443,093 - 138,455,499 (+)EnsemblGRCm38mm10GRCm38
GRCm383138,437,200 - 138,455,499 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373138,106,128 - 138,118,463 (+)NCBIGRCm37mm9NCBIm37
MGSCv363138,380,551 - 138,392,886 (+)NCBImm8
Celera3144,865,856 - 144,878,188 (+)NCBICelera
Cytogenetic Map3G3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Adh5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1615209
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.