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Gene: Adh5 (alcohol dehydrogenase 5 (class III), chi polypeptide) Mus musculus
Symbol: Adh5
Name: alcohol dehydrogenase 5 (class III), chi polypeptide
Description: Exhibits S-(hydroxymethyl)glutathione dehydrogenase activity; alcohol dehydrogenase (NAD+) activity; and identical protein binding activity. Involved in several processes, including formaldehyde catabolic process; peptidyl-cysteine S-nitrosylation; and response to lipopolysaccharide. Localizes to mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and respiratory system. Human ortholog(s) of this gene implicated in asthma. Orthologous to human ADH5 (alcohol dehydrogenase 5 (class III), chi polypeptide); PARTICIPATES IN gluconeogenesis pathway; glycolysis pathway; glycolysis/gluconeogenesis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Adh-5; ADH-B2; Adh3; alcohol dehydrogenase 2; alcohol dehydrogenase B2; alcohol dehydrogenase class-3; alcohol dehydrogenase class-III; FALDH; FDH; glutathione-dependent formaldehyde dehydrogenase; GSH-FDH; GSNOR; S-(hydroxymethyl)glutathione dehydrogenase; S-nitrosoglutathione reductase
Related Pseudogenes: Adh5-ps1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl3138,443,093 - 138,455,499 (+)EnsemblGRCm38mm10GRCm38
GRCm383138,437,200 - 138,455,499 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373138,106,128 - 138,118,463 (+)NCBIGRCm37mm9NCBIm37
MGSCv363138,380,551 - 138,392,886 (+)NCBImm8
Celera3144,865,856 - 144,878,188 (+)NCBICelera
Cytogenetic Map3G3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Adh5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1615209
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.