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Gene: Lemd3 (LEM domain containing 3) Mus musculus
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Symbol: Lemd3
Name: LEM domain containing 3
Description: Predicted to have DNA binding activity. Involved in several processes, including blood vessel endothelial cell migration involved in intussusceptive angiogenesis; regulation of extracellular matrix organization; and skeletal muscle cell differentiation. Localizes to the nuclear envelope. Is expressed in several structures, including allantois; foregut diverticulum endoderm; lateral plate mesoderm; neural plate; and primitive streak. Orthologous to human LEMD3 (LEM domain containing 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI316861; inner nuclear membrane protein Man1; integral inner nuclear membrane protein MAN1; LEM domain-containing protein 3; Man1
Orthologs:
Homo sapiens (human) : LEMD3 (LEM domain containing 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lemd3 (LEM domain containing 3)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LEMD3 (LEM domain containing 3)
Canis lupus familiaris (dog) : LEMD3 (LEM domain containing 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lemd3 (LEM domain containing 3)
Sus scrofa (pig) : LEMD3 (LEM domain containing 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3810120,923,411 - 120,979,396 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710120,360,467 - 120,416,386 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610120,326,471 - 120,382,392 (-)NCBImm8
Celera10123,286,658 - 123,342,549 (-)NCBICelera
Cytogenetic Map10 D2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Lemd3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1615524
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.