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Gene: Syne2 (spectrin repeat containing, nuclear envelope 2) Mus musculus
Symbol: Syne2
Name: spectrin repeat containing, nuclear envelope 2
Description: Exhibits actin binding activity. Involved in several processes, including fibroblast migration; nuclear migration; and regulation of cilium assembly. Localizes to the nuclear outer membrane. Colocalizes with the Z disc. Human ortholog(s) of this gene implicated in autosomal dominant Emery-Dreifuss muscular dystrophy 5. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human SYNE2 (spectrin repeat containing nuclear envelope protein 2); INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6820443O06Rik; AW546258; Cpfl8; D12Ertd777e; dice; diminished cone electroretinogram; KASH domain-containing protein 2; KASH2; MGC96690; mKIAA1011; Nesp2g; nesprin 2; nesprin-2; NUA; nuance; nuclear envelope spectrin repeat protein 2; nucleus and actin connecting element protein; synaptic nuclear envelope 2; synaptic nuclear envelope protein 2
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1275,818,134 - 76,110,926 (+)EnsemblGRCm38mm10GRCm38
GRCm381275,818,318 - 76,110,928 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371276,919,305 - 77,211,915 (+)NCBIGRCm37mm9NCBIm37
MGSCv361276,772,909 - 77,029,768 (+)NCBImm8
Celera1276,923,010 - 77,205,661 (+)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1233.11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Syne2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1615570
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.