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Gene: Il27 (interleukin 27) Mus musculus
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Symbol: Il27
Name: interleukin 27
Description: Exhibits interleukin-27 receptor binding activity. Involved in positive regulation of defense response to virus by host and regulation of T cell proliferation. Localizes to extracellular space. Is expressed in decidua; embryo; and extraembryonic component. Human ortholog(s) of this gene implicated in asthma and chronic obstructive pulmonary disease. Orthologous to human IL27 (interleukin 27); PARTICIPATES IN interleukin-27 signaling pathway; INTERACTS WITH 4-hydroxynon-2-enal; benzalkonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: IL-27; IL-27 p28 subunit; IL-27 subunit alpha; IL-27-A; IL-27p28; IL27-A; Il30; interleukin 30; interleukin-27 subunit alpha; p28
Orthologs:
Homo sapiens (human) : IL27 (interleukin 27)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Il27 (interleukin 27)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il27 (interleukin 27)
Pan paniscus (bonobo/pygmy chimpanzee) : IL27 (interleukin 27)
Canis lupus familiaris (dog) : IL27 (interleukin 27)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il27 (interleukin 27)
Sus scrofa (pig) : IL27 (interleukin 27)
Chlorocebus sabaeus (African green monkey) : IL27 (interleukin 27)
Heterocephalus glaber (naked mole-rat) : Il27 (interleukin 27)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl7126,589,010 - 126,594,941 (-)EnsemblGRCm38mm10GRCm38
GRCm387126,589,009 - 126,595,035 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377133,732,809 - 133,738,424 (-)NCBIGRCm37mm9NCBIm37
MGSCv367126,380,443 - 126,386,058 (-)NCBImm8
Celera7126,438,423 - 126,444,039 (-)NCBICelera
Cytogenetic Map7F3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Il27
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1615620
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.