Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Il27 (interleukin 27) Mus musculus
Symbol: Il27
Name: interleukin 27
Description: Exhibits interleukin-27 receptor binding activity. Involved in positive regulation of defense response to virus by host and regulation of T cell proliferation. Localizes to extracellular space. Is expressed in decidua; embryo; and extraembryonic component. Human ortholog(s) of this gene implicated in asthma and chronic obstructive pulmonary disease. Orthologous to human IL27 (interleukin 27); PARTICIPATES IN interleukin-27 signaling pathway; INTERACTS WITH 4-hydroxynon-2-enal; benzalkonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: IL-27; IL-27 p28 subunit; IL-27 subunit alpha; IL-27-A; IL-27p28; IL27-A; Il30; interleukin 30; interleukin-27 subunit alpha; p28
Homo sapiens (human) : IL27 (interleukin 27)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Il27 (interleukin 27)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il27 (interleukin 27)
Pan paniscus (bonobo/pygmy chimpanzee) : IL27 (interleukin 27)
Canis lupus familiaris (dog) : IL27 (interleukin 27)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il27 (interleukin 27)
Sus scrofa (pig) : IL27 (interleukin 27)
Chlorocebus sabaeus (African green monkey) : IL27 (interleukin 27)
Heterocephalus glaber (naked mole-rat) : Il27 (interleukin 27)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl7126,589,010 - 126,594,941 (-)EnsemblGRCm38mm10GRCm38
GRCm387126,589,009 - 126,595,035 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377133,732,809 - 133,738,424 (-)NCBIGRCm37mm9NCBIm37
MGSCv367126,380,443 - 126,386,058 (-)NCBImm8
Celera7126,438,423 - 126,444,039 (-)NCBICelera
Cytogenetic Map7F3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Il27
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1615620
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.