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Gene: Dok7 (docking protein 7) Mus musculus
Symbol: Dok7
Name: docking protein 7
Description: Exhibits phosphatidylinositol binding activity and protein kinase binding activity. Involved in neuromuscular junction development; positive regulation of protein tyrosine kinase activity; and receptor clustering. Localizes to the neuromuscular junction. Used to study congenital myasthenic syndrome 10. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 10. Is expressed in several structures, including central nervous system; heart; skeletal muscle; and testis. Orthologous to human DOK7 (docking protein 7); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; INTERACTS WITH 1,2-dichloroethane; 4-hydroxyphenyl retinamide; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A930013K19Rik; AW049091; Dok-7; downstream of tyrosine kinase 7; EF-12; MGC107606; Oit5; oncoprotein induced transcript 5
Homo sapiens (human) : DOK7 (docking protein 7)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dok7 (docking protein 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dok7 (docking protein 7)
Pan paniscus (bonobo/pygmy chimpanzee) : DOK7 (docking protein 7)
Canis lupus familiaris (dog) : DOK7 (docking protein 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dok7 (docking protein 7)
Sus scrofa (pig) : DOK7 (docking protein 7)
Chlorocebus sabaeus (green monkey) : DOK7 (docking protein 7)
Heterocephalus glaber (naked mole-rat) : Dok7 (docking protein 7)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl535,056,766 - 35,087,839 (+)Ensembl
GRCm38535,056,571 - 35,087,839 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37535,399,733 - 35,430,480 (+)NCBIGRCm37mm9NCBIm37
MGSCv36535,373,945 - 35,404,692 (+)NCBImm8
Celera532,531,870 - 32,562,455 (+)NCBICelera
Cytogenetic Map5 B2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Dok7
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1615685
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.