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Gene: Arfgef1 (ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)) Mus musculus
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Symbol: Arfgef1
Name: ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)
Description: Predicted to have guanyl-nucleotide exchange factor activity; myosin binding activity; and protein kinase A regulatory subunit binding activity. Predicted to be involved in several processes, including negative regulation of GTPase activity; positive regulation of protein glycosylation in Golgi; and positive regulation of protein kinase B signaling. Predicted to localize to several cellular components, including the Golgi apparatus; nucleus; and perinuclear region of cytoplasm. Is expressed in brain. Orthologous to human ARFGEF1 (ADP ribosylation factor guanine nucleotide exchange factor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; atrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ADP-ribosylation factor guanine nucleotide-exchange factor 1; ARFGEP1; BIG1; brefeldin A-inhibited GEP 1; brefeldin A-inhibited guanine nucleotide-exchange protein 1; D130059B05Rik; D730028O18Rik; P200
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38110,137,507 - 10,232,670 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37110,127,588 - 10,222,751 (-)NCBIGRCm37mm9NCBIm37
MGSCv36110,122,721 - 10,218,159 (-)NCBImm8
Celera110,111,100 - 10,206,279 (-)NCBICelera
Cytogenetic Map1 A2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Arfgef1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1615720
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.