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Gene: Mael (maelstrom spermatogenic transposon silencer) Mus musculus
Symbol: Mael
Name: maelstrom spermatogenic transposon silencer
Description: Predicted to have sequence-specific DNA binding activity. Involved in several processes, including gamete generation; intrinsic apoptotic signaling pathway in response to DNA damage; and negative regulation of gene expression. Localizes to several cellular components, including chromosome; cytoplasmic ribonucleoprotein granule; and perinuclear region of cytoplasm. Is expressed in brain; early conceptus; and genitourinary system. Orthologous to human MAEL (maelstrom spermatogenic transposon silencer); INTERACTS WITH bis(2-ethylhexyl) phthalate; bisphenol A; (-)-epigallocatechin 3-gallate (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4933405K18Rik; AU019877; maelstrom homolog; protein maelstrom homolog
Homo sapiens (human) : MAEL (maelstrom spermatogenic transposon silencer)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mael (maelstrom spermatogenic transposon silencer)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mael (maelstrom spermatogenic transposon silencer)
Pan paniscus (bonobo/pygmy chimpanzee) : MAEL (maelstrom spermatogenic transposon silencer)
Canis lupus familiaris (dog) : MAEL (maelstrom spermatogenic transposon silencer)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mael (maelstrom spermatogenic transposon silencer)
Sus scrofa (pig) : MAEL (maelstrom spermatogenic transposon silencer)
Chlorocebus sabaeus (African green monkey) : MAEL (maelstrom spermatogenic transposon silencer)
Heterocephalus glaber (naked mole-rat) : Mael (maelstrom spermatogenic transposon silencer)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1166,201,201 - 166,238,747 (-)EnsemblGRCm38mm10GRCm38
GRCm381166,201,385 - 166,238,744 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371168,131,516 - 168,168,875 (-)NCBIGRCm37mm9NCBIm37
MGSCv361168,038,060 - 168,075,419 (-)NCBImm8
Celera1168,644,539 - 168,681,904 (-)NCBICelera
Cytogenetic Map1H2.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Mael
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1615781
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.