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Gene: Usp21 (ubiquitin specific peptidase 21) Mus musculus
Symbol: Usp21
Name: ubiquitin specific peptidase 21
Description: Exhibits thiol-dependent ubiquitinyl hydrolase activity and transcription coactivator activity. Involved in histone deubiquitination and positive regulation of transcription, DNA-templated. Predicted to localize to cytosol; nucleoplasm; and plasma membrane. Is expressed in left lung; right lung; and submandibular gland primordium. Orthologous to human USP21 (ubiquitin specific peptidase 21); PARTICIPATES IN histone modification pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: deubiquitinating enzyme 21; ESTM28; ubiquitin carboxyl-terminal hydrolase 21; ubiquitin specific protease 21; ubiquitin specific protease 23; ubiquitin thioesterase 21; ubiquitin thiolesterase 21; ubiquitin-specific-processing protease 21; Usp16; Usp23; W53272
Homo sapiens (human) : USP21 (ubiquitin specific peptidase 21)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Usp21 (ubiquitin specific peptidase 21)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Usp21 (ubiquitin specific peptidase 21)
Pan paniscus (bonobo/pygmy chimpanzee) : USP21 (ubiquitin specific peptidase 21)
Canis lupus familiaris (dog) : USP21 (ubiquitin specific peptidase 21)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Usp21 (ubiquitin specific peptidase 21)
Sus scrofa (pig) : USP21 (ubiquitin specific peptidase 21)
Chlorocebus sabaeus (African green monkey) : USP21 (ubiquitin specific peptidase 21)
Heterocephalus glaber (naked mole-rat) : Usp21 (ubiquitin specific peptidase 21)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1171,281,945 - 171,287,991 (-)EnsemblGRCm38mm10GRCm38
GRCm381171,281,949 - 171,287,961 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371173,212,080 - 173,218,092 (-)NCBIGRCm37mm9NCBIm37
MGSCv361173,118,624 - 173,124,623 (-)NCBImm8
Celera1173,737,971 - 173,743,991 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Usp21
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1615930
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.