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Gene: Thbs1 (thrombospondin 1) Mus musculus
Symbol: Thbs1
Name: thrombospondin 1
Description: Exhibits extracellular matrix binding activity. Involved in several processes, including cellular response to nitric oxide; circulatory system development; and positive regulation of macrophage chemotaxis. Localizes to the extracellular space and sarcoplasmic reticulum. Used to study Sjogren's syndrome. Human ortholog(s) of this gene implicated in cholangiocarcinoma; pancreatic cancer; and pancreatic ductal carcinoma. Is expressed in several structures, including brain; limb; respiratory system; sensory organ; and skeleton. Orthologous to human THBS1 (thrombospondin 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: glycoprotein G; tbsp1; Thbs-1; thrombospondin-1; TSP-1; TSP1
Homo sapiens (human) : THBS1 (thrombospondin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Thbs1 (thrombospondin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Thbs1 (thrombospondin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : THBS1 (thrombospondin 1)
Canis lupus familiaris (dog) : THBS1 (thrombospondin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Thbs1 (thrombospondin 1)
Sus scrofa (pig) : THBS1 (thrombospondin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm382118,111,876 - 118,127,133 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372117,937,658 - 117,952,869 (+)NCBIGRCm37mm9NCBIm37
MGSCv362119,046,897 - 119,061,990 (+)NCBImm8
MGSCv362117,803,363 - 117,818,574 (+)NCBImm8
Celera2119,257,347 - 119,271,479 (+)NCBICelera
Cytogenetic Map2 E5NCBI
cM Map259.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Thbs1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1615939
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-11-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.