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Gene: Thbs1 (thrombospondin 1) Mus musculus
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Symbol: Thbs1
Name: thrombospondin 1
Description: Exhibits extracellular matrix binding activity. Involved in several processes, including cellular response to nitric oxide; circulatory system development; and positive regulation of macrophage chemotaxis. Localizes to the extracellular space and sarcoplasmic reticulum. Used to study Sjogren's syndrome. Human ortholog(s) of this gene implicated in cholangiocarcinoma; pancreatic cancer; and pancreatic ductal carcinoma. Is expressed in several structures, including brain; limb; respiratory system; sensory organ; and skeleton. Orthologous to human THBS1 (thrombospondin 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: glycoprotein G; tbsp1; Thbs-1; thrombospondin-1; TSP-1; TSP1
Orthologs:
Homo sapiens (human) : THBS1 (thrombospondin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Thbs1 (thrombospondin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Thbs1 (thrombospondin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : THBS1 (thrombospondin 1)
Canis lupus familiaris (dog) : THBS1 (thrombospondin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Thbs1 (thrombospondin 1)
Sus scrofa (pig) : THBS1 (thrombospondin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm382118,111,876 - 118,127,133 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372117,937,658 - 117,952,869 (+)NCBIGRCm37mm9NCBIm37
MGSCv362119,046,897 - 119,061,990 (+)NCBImm8
MGSCv362117,803,363 - 117,818,574 (+)NCBImm8
Celera2119,257,347 - 119,271,479 (+)NCBICelera
Cytogenetic Map2 E5NCBI
cM Map259.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Thbs1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1615939
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-11-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.