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Gene: Ptch2 (patched 2) Mus musculus
Symbol: Ptch2
Name: patched 2
CRRD ID: 1615950
Description: Predicted to have hedgehog family protein binding activity; hedgehog receptor activity; and smoothened binding activity. Involved in several processes, including epidermal cell fate specification; hair cycle; and positive regulation of epidermal cell differentiation. Predicted to localize to plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and sensory organ. Human ortholog(s) of this gene implicated in basal cell carcinoma; medulloblastoma; and nevoid basal cell carcinoma syndrome. Orthologous to human PTCH2 (patched 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: patched homolog 2; protein patched homolog 2; ptc; ptc2
Homo sapiens (human) : PTCH2 (patched 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ptch2 (patched 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptch2 (patched 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PTCH2 (patched 2)
Canis lupus familiaris (dog) : PTCH2 (patched 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptch2 (patched 2)
Sus scrofa (pig) : PTCH2 (patched 2)
Chlorocebus sabaeus (African green monkey) : PTCH2 (patched 2)
Heterocephalus glaber (naked mole-rat) : Ptch2 (patched 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm394116,953,253 - 116,973,298 (+)NCBI
GRCm384117,096,056 - 117,116,101 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4117,096,075 - 117,116,101 (+)EnsemblGRCm38mm10GRCm38
MGSCv374116,768,961 - 116,787,436 (+)NCBIGRCm37mm9NCBIm37
MGSCv364116,594,288 - 116,612,763 (+)NCBImm8
MGSCv364114,859,487 - 114,878,450 (+)NCBImm8
Celera4115,831,925 - 115,852,375 (+)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.41NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Ptch2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1615950
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-11-17
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.