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Gene: Ptch2 (patched 2) Mus musculus
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Symbol: Ptch2
Name: patched 2
CRRD ID: 1615950
Description: Predicted to have hedgehog family protein binding activity; hedgehog receptor activity; and smoothened binding activity. Involved in several processes, including epidermal cell fate specification; hair cycle; and positive regulation of epidermal cell differentiation. Predicted to localize to plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and sensory organ. Human ortholog(s) of this gene implicated in basal cell carcinoma; medulloblastoma; and nevoid basal cell carcinoma syndrome. Orthologous to human PTCH2 (patched 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: patched homolog 2; protein patched homolog 2; ptc; ptc2
Orthologs:
Homo sapiens (human) : PTCH2 (patched 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ptch2 (patched 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptch2 (patched 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PTCH2 (patched 2)
Canis lupus familiaris (dog) : PTCH2 (patched 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptch2 (patched 2)
Sus scrofa (pig) : PTCH2 (patched 2)
Chlorocebus sabaeus (African green monkey) : PTCH2 (patched 2)
Heterocephalus glaber (naked mole-rat) : Ptch2 (patched 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394116,953,253 - 116,973,298 (+)NCBI
GRCm384117,096,056 - 117,116,101 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4117,096,075 - 117,116,101 (+)EnsemblGRCm38mm10GRCm38
MGSCv374116,768,961 - 116,787,436 (+)NCBIGRCm37mm9NCBIm37
MGSCv364116,594,288 - 116,612,763 (+)NCBImm8
MGSCv364114,859,487 - 114,878,450 (+)NCBImm8
Celera4115,831,925 - 115,852,375 (+)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Ptch2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1615950
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-11-17
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.