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Gene: Kdm2a (lysine (K)-specific demethylase 2A) Mus musculus
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Symbol: Kdm2a
Name: lysine (K)-specific demethylase 2A
Description: Exhibits unmethylated CpG binding activity. Involved in several processes, including chordate embryonic development; growth; and positive regulation of macromolecule metabolic process. Localizes to the nuclear chromatin. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Is expressed in embryo; forebrain; and limb. Orthologous to human KDM2A (lysine demethylase 2A); PARTICIPATES IN DNA modification pathway; histone modification pathway; INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 100043628; 5530401A10Rik; [Histone-H3]-lysine-36 demethylase 1A; AA589516; AW536790; Cxxc8; expressed sequence AA589516; expressed sequence AW536790; F-box and leucine-rich repeat protein 11; F-box protein containing leucine repeats; F-box/LRR-repeat protein 11; Fbl11; Fbl7; Fbxl11; Gm4560; hypothetical protein LOC71431; Jhdm1; Jhdm1a; jmjC domain-containing histone demethylation protein 1A; lalina; lysine-specific demethylase 2A; predicted gene 4560; RIKEN cDNA 5530401A10 gene
Orthologs:
Homo sapiens (human) : KDM2A (lysine demethylase 2A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kdm2a (lysine demethylase 2A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm2a (lysine demethylase 2A)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM2A (lysine demethylase 2A)
Canis lupus familiaris (dog) : KDM2A (lysine demethylase 2A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm2a (lysine demethylase 2A)
Sus scrofa (pig) : KDM2A (lysine demethylase 2A)
Chlorocebus sabaeus (African green monkey) : KDM2A (lysine demethylase 2A)
Heterocephalus glaber (naked mole-rat) : Kdm2a (lysine demethylase 2A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl194,314,419 - 4,398,285 (-)EnsemblGRCm38mm10GRCm38
GRCm38194,316,144 - 4,398,721 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37194,316,144 - 4,397,077 (-)NCBIGRCm37mm9NCBIm37
MGSCv36194,317,806 - 4,398,266 (-)NCBImm8
Celera194,187,040 - 4,267,780 (-)NCBICelera
Cytogenetic Map19ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Kdm2a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1616561
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.