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Gene: Ago3 (argonaute RISC catalytic subunit 3) Mus musculus
Symbol: Ago3
Name: argonaute RISC catalytic subunit 3
Description: Exhibits RNA binding activity. Involved in positive regulation of NIK/NF-kappaB signaling and positive regulation of gene expression. Localizes to RISC complex and condensed nuclear chromosome. Is expressed in several structures, including central nervous system; early embryo; lung mesenchyme; sensory organ; and trunk somite. Orthologous to human AGO3 (argonaute RISC catalytic component 3); PARTICIPATES IN microRNA pathway; INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxynon-2-enal.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: argonaute 3; argonaute RISC catalytic component 3; argonaute3; AW048688; C130014L07Rik; eIF-2C 3; eIF2C 3; Eif2c3; eukaryotic translation initiation factor 2C, 3; mAgo3; Piwi/Argonaute family protein meIF2C3; protein argonaute-3
Homo sapiens (human) : AGO3 (argonaute RISC catalytic component 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ago3 (argonaute RISC catalytic component 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ago3 (argonaute RISC catalytic component 3)
Pan paniscus (bonobo/pygmy chimpanzee) : AGO3 (argonaute RISC catalytic component 3)
Canis lupus familiaris (dog) : AGO3 (argonaute RISC catalytic component 3)
Sus scrofa (pig) : AGO3 (argonaute RISC catalytic component 3)
Chlorocebus sabaeus (African green monkey) : AGO3 (argonaute RISC catalytic component 3)
Heterocephalus glaber (naked mole-rat) : Ago3 (argonaute RISC catalytic component 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl4126,331,704 - 126,429,556 (-)EnsemblGRCm38mm10GRCm38
GRCm384126,326,994 - 126,431,670 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374126,017,922 - 126,106,786 (-)NCBIGRCm37mm9NCBIm37
MGSCv364125,847,689 - 125,931,698 (-)NCBImm8
Celera4124,677,462 - 124,766,345 (-)NCBICelera
Cytogenetic Map4D2.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Ago3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1616587
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.