Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Sem1 (SEM1, 26S proteasome complex subunit) Mus musculus
Symbol: Sem1
Name: SEM1, 26S proteasome complex subunit
CRRD ID: 1616831
Description: Involved in double-strand break repair via homologous recombination. Predicted to colocalize with integrator complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human SEM1 (SEM1 26S proteasome complex subunit); PARTICIPATES IN homologous recombination pathway of double-strand break repair; ubiquitin/proteasome degradation pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 26S proteasome complex subunit DSS1; 26S proteasome complex subunit SEM1; deleted in split hand/split foot protein 1 homolog; DS; DSS1; Shf; Shfdg; Shfdg1; Shfg; Shfm; Shfm1; split hand/foot deleted gene 1; split hand/foot deleted protein 1 homolog; split hand/foot malformation (ectrodactyly) type 1; split hand/foot malformation type 1 protein homolog
Homo sapiens (human) : SEM1 (SEM1 26S proteasome complex subunit)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sem1 (SEM1, 26S proteasome complex subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sem1 (SEM1 26S proteasome complex subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : SEM1 (SEM1, 26S proteasome complex subunit)
Canis lupus familiaris (dog) : SEM1 (SEM1, 26S proteasome complex subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sem1 (SEM1 26S proteasome complex subunit)
Sus scrofa (pig) : SEM1 (SEM1 26S proteasome complex subunit)
Chlorocebus sabaeus (African green monkey) : SEM1 (SEM1 26S proteasome complex subunit)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm3966,558,275 - 6,578,658 (-)NCBI
GRCm3866,558,275 - 6,578,658 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl66,557,294 - 6,578,663 (-)EnsemblGRCm38mm10GRCm38
MGSCv3766,508,275 - 6,528,658 (-)NCBIGRCm37mm9NCBIm37
MGSCv3666,508,288 - 6,528,592 (-)NCBImm8
Celera66,710,797 - 6,731,239 (-)NCBICelera
Cytogenetic Map6A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Sem1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1616831
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.