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Gene: Myh2 (myosin, heavy polypeptide 2, skeletal muscle, adult) Mus musculus
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Symbol: Myh2
Name: myosin, heavy polypeptide 2, skeletal muscle, adult
Description: Involved in actin-mediated cell contraction; plasma membrane repair; and response to activity. Localizes to several cellular components, including A band; Golgi apparatus; and actomyosin contractile ring. Is expressed in several structures, including alimentary system; forelimb bud mesenchyme; and skeletal musculature. Human ortholog(s) of this gene implicated in inclusion body myositis. Orthologous to human MYH2 (myosin heavy chain 2); PARTICIPATES IN myocarditis pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 17beta-hydroxy-5alpha-androstan-3-one.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MHC2A; Myh2a; MyHC-IIa; Myhs-f; Myhs-f1; Myhsf1; myosin heavy chain 2A; myosin heavy chain IIa; myosin-2; skeletal muscle myosin heavy chain II-a
Orthologs:
Homo sapiens (human) : MYH2 (myosin heavy chain 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Myh2 (myosin heavy chain 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myh2 (myosin heavy chain 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MYH2 (myosin heavy chain 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myh2 (myosin heavy chain 2)
Sus scrofa (pig) : MYH2 (myosin, heavy chain 2, skeletal muscle, adult)
Chlorocebus sabaeus (African green monkey) : MYH2 (myosin heavy chain 2)
Heterocephalus glaber (naked mole-rat) : Myh2 (myosin heavy chain 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1167,171,027 - 67,197,517 (+)EnsemblGRCm38mm10GRCm38
GRCm381167,171,027 - 67,197,517 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371166,984,529 - 67,011,019 (+)NCBIGRCm37mm9NCBIm37
MGSCv361166,987,415 - 67,013,709 (+)NCBImm8
Celera1174,109,947 - 74,136,336 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1140.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Myh2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1616843
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-07-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.