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Gene: Hells (helicase, lymphoid specific) Mus musculus
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Symbol: Hells
Name: helicase, lymphoid specific
Description: Exhibits chromatin binding activity. Involved in several processes, including DNA metabolic process; cellular response to leukemia inhibitory factor; and chromatin organization involved in negative regulation of transcription. Localizes to nucleus and pericentric heterochromatin. Is expressed in several structures, including central nervous system; gut; neural retina; reproductive system; and thymus. Human ortholog(s) of this gene implicated in immunodeficiency-centromeric instability-facial anomalies syndrome 4. Orthologous to human HELLS (helicase, lymphoid specific); INTERACTS WITH (S)-nicotine; 1,2-dichloroethane; 1,4-dioxane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI323785; E130115I21Rik; LSH; lymphocyte-specific helicase; Lysh; PASG; proliferation-associated SNF2-like protein; YFK8
Orthologs:
Homo sapiens (human) : HELLS (helicase, lymphoid specific)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hells (helicase, lymphoid specific)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hells (helicase, lymphoid specific)
Pan paniscus (bonobo/pygmy chimpanzee) : HELLS (helicase, lymphoid specific)
Canis lupus familiaris (dog) : HELLS (helicase, lymphoid specific)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hells (helicase, lymphoid specific)
Sus scrofa (pig) : HELLS (helicase, lymphoid specific)
Chlorocebus sabaeus (African green monkey) : HELLS (helicase, lymphoid specific)
Heterocephalus glaber (naked mole-rat) : Hells (helicase, lymphoid specific)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1938,930,915 - 38,971,051 (+)EnsemblGRCm38mm10GRCm38
GRCm381938,930,262 - 38,970,470 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371939,005,480 - 39,042,767 (+)NCBIGRCm37mm9NCBIm37
MGSCv361938,996,134 - 39,033,421 (+)NCBImm8
Celera1939,732,380 - 39,769,659 (+)NCBICelera
Cytogenetic Map19C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hells
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1616865
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-06-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.