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Gene: H2-M5 (histocompatibility 2, M region locus 5) Mus musculus
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Symbol: H2-M5
Name: histocompatibility 2, M region locus 5
CRRD ID: 1617322
Description: Predicted to have peptide antigen binding activity and signaling receptor binding activity. Predicted to be involved in several processes, including antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; antigen processing and presentation of endogenous peptide antigen via MHC class Ib; and positive regulation of T cell mediated cytotoxicity. Predicted to localize to external side of plasma membrane and extracellular space. Is expressed in brain and thymus. Human ortholog(s) of this gene implicated in asthma and hepatitis C. Orthologous to human HLA-E (major histocompatibility complex, class I, E); HLA-F (major histocompatibility complex, class I, F); and HLA-G (major histocompatibility complex, class I, G); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CRW; CRW2; D130003B22Rik; H-2M5; MHC class I like protein M5; MHC classIb protein M5
Orthologs:
Rattus norvegicus (Norway rat) : RT1-M5 (RT1 class Ib, locus M5)  Alliance
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391737,294,677 - 37,308,847 (-)NCBI
GRCm381736,983,785 - 36,997,955 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1736,984,061 - 36,989,537 (-)EnsemblGRCm38mm10GRCm38
MGSCv371737,123,800 - 37,126,449 (-)NCBIGRCm37mm9NCBIm37
MGSCv361736,595,031 - 36,597,557 (-)NCBImm8
Celera1740,410,376 - 40,413,023 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1719.16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on H2-M5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1617322
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.