Btnl1 (butyrophilin-like 1) - Chinchilla Research Resource Database
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Gene: Btnl1 (butyrophilin-like 1) Mus musculus
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Symbol: Btnl1
Name: butyrophilin-like 1
CRRD ID: 1617324
Description: Predicted to have signaling receptor binding activity. Involved in extrathymic T cell selection. Localizes to cell surface. Is expressed in ductus deferens; epididymis; ileum; prostate gland; and testis. Orthologous to human BTNL3 (butyrophilin like 3) and BTNL8 (butyrophilin like 8); INTERACTS WITH chromium(6+); ozone; potassium dichromate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Btn; Btnl3; butyrophilin-like 3; butyrophilin-like protein 1; Gm316; Gm33; MGC56990; NG1; NG10
Orthologs:
No known orthologs. homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,596,097 - 34,605,136 (+)NCBI
GRCm381734,377,123 - 34,386,162 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,377,132 - 34,386,028 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,514,077 - 34,522,973 (+)NCBIGRCm37mm9NCBIm37
MGSCv361734,514,097 - 34,522,973 (+)NCBImm8
Celera1737,145,630 - 37,154,526 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10803852   PMID:12040188   PMID:12477932   PMID:15489334   PMID:20944003   PMID:21368163   PMID:21873635   PMID:24194600   PMID:27528202   PMID:27626380   PMID:27641500   PMID:32724083  


Genomics

Position Markers
px-61c4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381734,376,283 - 34,376,398UniSTSGRCm38
MGSCv371734,513,228 - 34,513,343UniSTSGRCm37
Celera1737,144,781 - 37,144,896UniSTS
Cytogenetic Map17B1UniSTS
cM Map1718.7UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
CRRD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17312791337128037Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17392461548559063Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined480447745359340Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17480447746158776Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17480447747574740Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined480447765330362Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17667496240674962Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17836594042366175Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17836594042366175Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined17986241186688972Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171065914544659245Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1098759739053168Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1166699745667145Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171177921045779210Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171206732483054339Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171223281346232813Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171242798746427987Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171390439847904522Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171484267848842786Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171484267848842786Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171484267848842786Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171484267848842786Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171660074750600869Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171660074750600869Mouse
1301505Tir1_mtrypanosome infection response 1 (mouse)Not determined171660074750600869Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171681096950811104Mouse
1302042Acsns3_mAngiostrongylus costaricensis nematode susceptibility 3 (mouse)Not determined171724323451243371Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171724323451243371Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171724323451243371Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171724323451243371Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171724323451243371Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171795643651959238Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171819938152202007Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171820316552205351Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171883413352834133Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172430185958301973Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172485760955405969Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172536594043665344Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172574029459740461Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172618203852604676Mouse
1300602Eye2_meye weight 2 (mouse)Not determined172628636340794146Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172657408160574223Mouse
11075105Modc1_mmodifier of Odc1 (mouse)172749681845311728Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172750432261504322Mouse
10045977Tir9_mtrypanosome infection response 9 (mouse)Not determined172765914543574223Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172831148062311728Mouse
11038694Pas19_mpulmonary adenoma susceptibility 19 (mouse)172949219034535463Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined172982162963821740Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3072257564722705Mouse
4141357Mrdq1_mmodifier of retinal degeneration QTL 1 (mouse)Not determined3076892947728778Mouse
1300692Blmpf1_mbleomycin-induced pulmonary fibrosis 1 (mouse)Not determined173184267837333884Mouse
25394538Skmw84_mskeletal muscle weight 84, TA (mouse)173244145235301060Mouse
26884379Skwq5_mskull length QTL 5, 5 week (mouse)173290000053800000Mouse
1302189Dps3_mdelta power in slow-wave sleep 3 (mouse)Not determined173360074735939288Mouse
1301759Sles1_msystemic lupus erythmatosus suppressor 1 (mouse)Not determined173400091634956961Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:206
Count of miRNA genes:194
Interacting mature miRNAs:206
Transcripts:ENSMUST00000080254
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000080254   ⟹   ENSMUSP00000079140
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1734,377,132 - 34,386,028 (+)Ensembl
RefSeq Acc Id: ENSMUST00000236230
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1734,377,886 - 34,381,198 (+)Ensembl
RefSeq Acc Id: NM_001111094   ⟹   NP_001104564
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391734,596,106 - 34,605,002 (+)NCBI
GRCm381734,377,132 - 34,386,028 (+)NCBI
MGSCv371734,514,077 - 34,522,973 (+)RGD
Celera1737,145,630 - 37,154,526 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006523364   ⟹   XP_006523427
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391734,596,097 - 34,605,136 (+)NCBI
GRCm381734,377,123 - 34,386,162 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001104564   ⟸   NM_001111094
- Peptide Label: precursor
- UniProtKB: Q7TST0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006523427   ⟸   XM_006523364
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000079140   ⟸   ENSMUST00000080254
Protein Domains
B30.2/SPRY   Ig-like V-type

Promoters
RGD ID:13675694
Promoter ID:EPDNEW_M21996
Type:initiation region
Name:Btnl1_1
Description:Mus musculus butyrophilin-like 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381734,377,132 - 34,377,192EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1932027 AgrOrtholog
Ensembl Genes ENSMUSG00000062638 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000079140 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000080254 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.920 UniProtKB/Swiss-Prot
  2.60.40.10 UniProtKB/Swiss-Prot
InterPro B30.2/SPRY UniProtKB/Swiss-Prot
  B30.2/SPRY_sf UniProtKB/Swiss-Prot
  Butyrophylin_SPRY UniProtKB/Swiss-Prot
  ConA-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_V-set UniProtKB/Swiss-Prot
  SPRY_dom UniProtKB/Swiss-Prot
KEGG Report mmu:100038862 UniProtKB/Swiss-Prot
MGD MGI:1932027 ENTREZGENE
NCBI Gene 100038862 ENTREZGENE
Pfam SPRY UniProtKB/Swiss-Prot
  V-set UniProtKB/Swiss-Prot
PhenoGen Btnl1 PhenoGen
PRINTS BUTYPHLNCDUF UniProtKB/Swiss-Prot
PROSITE B302_SPRY UniProtKB/Swiss-Prot
  IG_LIKE UniProtKB/Swiss-Prot
SMART IGv UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
  SSF49899 UniProtKB/Swiss-Prot
UniGene Mm.440426 ENTREZGENE
UniProt BTNL1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A6X8K2 UniProtKB/Swiss-Prot
  G3UZN0 UniProtKB/Swiss-Prot
  O70356 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-04-03 Btnl1  butyrophilin-like 1  Btnl3  butyrophilin-like 3  Symbol and/or name change 5135510 APPROVED
2011-07-27 Btnl3  butyrophilin-like 3  Btnl1  butyrophilin-like 1  Symbol and/or name change 5135510 APPROVED