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Gene: Dnah1 (dynein, axonemal, heavy chain 1) Mus musculus
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Symbol: Dnah1
Name: dynein, axonemal, heavy chain 1
Description: Predicted to have ATP-dependent microtubule motor activity, minus-end-directed; dynein intermediate chain binding activity; and dynein light intermediate chain binding activity. Involved in cilium movement involved in cell motility; epithelial cilium movement involved in extracellular fluid movement; and flagellated sperm motility. Localizes to the sperm flagellum. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 37 and spermatogenic failure 18. Is expressed in cerebellum; choroid plexus; and lateral ventricle choroid plexus. Orthologous to human DNAH1 (dynein axonemal heavy chain 1); PARTICIPATES IN Huntington's disease pathway; INTERACTS WITH bis(2-ethylhexyl) phthalate; GW 4064; pentachlorophenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: axonemal beta dynein heavy chain 1; B230373P09Rik; ciliary dynein heavy chain 1; DKFZp434A236; Dnahc1; dynein heavy chain 1, axonemal; dynein, axon, heavy chain 1; dynein, axonemal, heavy polypeptide 1; E030034C22Rik; MDHC7; MGC37121; RIKEN cDNA B230373P09 gene
Orthologs:
Homo sapiens (human) : DNAH1 (dynein axonemal heavy chain 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dnah1 (dynein, axonemal, heavy chain 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dnah1 (dynein axonemal heavy chain 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DNAH1 (dynein axonemal heavy chain 1)
Canis lupus familiaris (dog) : DNAH1 (dynein axonemal heavy chain 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dnah1 (dynein axonemal heavy chain 1)
Sus scrofa (pig) : DNAH1 (dynein axonemal heavy chain 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381431,260,375 - 31,325,891 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371432,073,561 - 32,137,082 (-)NCBIGRCm37mm9NCBIm37
MGSCv361430,089,384 - 30,152,900 (-)NCBImm8
Celera1427,518,985 - 27,582,573 (-)NCBICelera
Cytogenetic Map14 BNCBI
cM Map1419.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Dnah1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1617422
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.