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Gene: Dnah1 (dynein, axonemal, heavy chain 1) Mus musculus
Symbol: Dnah1
Name: dynein, axonemal, heavy chain 1
Description: Predicted to have ATP-dependent microtubule motor activity, minus-end-directed; dynein intermediate chain binding activity; and dynein light intermediate chain binding activity. Involved in cilium movement involved in cell motility; epithelial cilium movement involved in extracellular fluid movement; and flagellated sperm motility. Localizes to the sperm flagellum. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 37 and spermatogenic failure 18. Is expressed in cerebellum; choroid plexus; and lateral ventricle choroid plexus. Orthologous to human DNAH1 (dynein axonemal heavy chain 1); PARTICIPATES IN Huntington's disease pathway; INTERACTS WITH bis(2-ethylhexyl) phthalate; GW 4064; pentachlorophenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: axonemal beta dynein heavy chain 1; B230373P09Rik; ciliary dynein heavy chain 1; DKFZp434A236; Dnahc1; dynein heavy chain 1, axonemal; dynein, axon, heavy chain 1; dynein, axonemal, heavy polypeptide 1; E030034C22Rik; MDHC7; MGC37121; RIKEN cDNA B230373P09 gene
Homo sapiens (human) : DNAH1 (dynein axonemal heavy chain 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dnah1 (dynein, axonemal, heavy chain 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dnah1 (dynein axonemal heavy chain 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DNAH1 (dynein axonemal heavy chain 1)
Canis lupus familiaris (dog) : DNAH1 (dynein axonemal heavy chain 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dnah1 (dynein axonemal heavy chain 1)
Sus scrofa (pig) : DNAH1 (dynein axonemal heavy chain 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381431,260,375 - 31,325,891 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371432,073,561 - 32,137,082 (-)NCBIGRCm37mm9NCBIm37
MGSCv361430,089,384 - 30,152,900 (-)NCBImm8
Celera1427,518,985 - 27,582,573 (-)NCBICelera
Cytogenetic Map14 BNCBI
cM Map1419.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Dnah1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1617422
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.