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Gene: H2-Q7 (histocompatibility 2, Q region locus 7) Mus musculus
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Symbol: H2-Q7
Name: histocompatibility 2, Q region locus 7
Description: Predicted to have several functions, including TAP complex binding activity; beta-2-microglobulin binding activity; and signaling receptor binding activity. Involved in cellular response to interferon-gamma and embryo implantation. Predicted to localize to several cellular components, including the Golgi medial cisterna; MHC class I protein complex; and endoplasmic reticulum. Human ortholog(s) of this gene implicated in Stevens-Johnson syndrome. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system gland; liver; and small intestine. Orthologous to human HLA-A (major histocompatibility complex, class I, A); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; autoimmune thyroiditis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; all-trans-retinoic acid; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: class Ib MHC antigen Qa-2; H-2 class I histocompatibility antigen, Q7 alpha chain; H-2Q7; Ped; Q9; Qa-2; QA-2 antigen; Qa-7; Qa7
Orthologs:
No known orthologs. homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381735,439,140 - 35,443,773 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv361735,047,269 - 35,051,696 (+)NCBImm8
Cytogenetic Map17 B1NCBI
cM Map1718.67NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on H2-Q7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1618429
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.