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Gene: Ms4a1 (membrane-spanning 4-domains, subfamily A, member 1) Mus musculus
Symbol: Ms4a1
Name: membrane-spanning 4-domains, subfamily A, member 1
Description: Predicted to have epidermal growth factor receptor binding activity and immunoglobulin binding activity. Involved in calcium ion import into cytosol and response to bacterium. Localizes to the external side of plasma membrane. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human MS4A1 (membrane spanning 4-domains A1); INTERACTS WITH 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA960661; B-cell differentiation antigen Ly-44; B-lymphocyte antigen CD20; Cd20; CD20 antigen; Ly-44; lymphocyte antigen 44; membrane-spanning 4-domains subfamily A member 1; membrane-spanning 4-domains, subfamily A, member 2; Ms4a2
Homo sapiens (human) : MS4A1 (membrane spanning 4-domains A1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ms4a1 (membrane spanning 4-domains A1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ms4a1 (membrane spanning 4-domains A1)
Pan paniscus (bonobo/pygmy chimpanzee) : MS4A1 (membrane spanning 4-domains A1)
Canis lupus familiaris (dog) : MS4A1 (membrane spanning 4-domains A1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ms4a1 (membrane spanning 4-domains A1)
Sus scrofa (pig) : MS4A1 (membrane spanning 4-domains A1)
Chlorocebus sabaeus (green monkey) : MS4A1 (membrane spanning 4-domains A1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1911,249,675 - 11,266,241 (-)Ensembl
GRCm381911,249,679 - 11,266,149 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371911,325,093 - 11,340,641 (-)NCBIGRCm37mm9NCBIm37
MGSCv361911,316,865 - 11,333,194 (-)NCBImm8
Celera1911,933,232 - 11,941,389 (-)NCBICelera
Cytogenetic Map19 ANCBI
cM Map198.19NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ms4a1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1618435
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.